Literature DB >> 3498127

Positron emission tomography studies of normal aging: a replication of PET III and 18-FDG using PET VI and 11-CDG.

M J de Leon, A E George, J Tomanelli, D Christman, A Kluger, J Miller, S H Ferris, J Fowler, J D Brodie, P van Gelder.   

Abstract

Using PET VI and 11-CDG we replicated our earlier PET III and 18-FDG normal aging findings. Examination of young and old normal volunteers revealed the absence of any absolute regional age-related changes in glucose utilization. For the combined sample (N = 81) we did find evidence to suggest a relative hypofrontal change with increasing age. A strong relationship between age and ventricular size (CT) was also found. These findings suggest the preserved glucose metabolism of the resting aging brain in the presence of structural atrophic changes.

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Year:  1987        PMID： 3498127     DOI： 10.1016/0197-4580(87)90070-4

Source DB:  PubMed          Journal:  Neurobiol Aging        ISSN： 0197-4580            Impact factor:   4.673


  13 in total

1.  Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/poitron-emission tomography (FDG/PET).

Authors:  M J de Leon; A Convit; O T Wolf; C Y Tarshish; S DeSanti; H Rusinek; W Tsui; E Kandil; A J Scherer; A Roche; A Imossi; E Thorn; M Bobinski; C Caraos; P Lesbre; D Schlyer; J Poirier; B Reisberg; J Fowler
Journal:  Proc Natl Acad Sci U S A       Date:  2001-08-28       Impact factor: 11.205

2.  Age-related metabolic profiles in cognitively healthy elders: results from a voxel-based [18F]fluorodeoxyglucose-positron-emission tomography study with partial volume effects correction.

Authors:  P K Curiati; J H Tamashiro-Duran; F L S Duran; C A Buchpiguel; P Squarzoni; D C Romano; H Vallada; P R Menezes; M Scazufca; G F Busatto; T C T F Alves
Journal:  AJNR Am J Neuroradiol       Date:  2011-01-27       Impact factor: 3.825

3.  Cognitive reserve modulates functional brain responses during memory tasks: a PET study in healthy young and elderly subjects.

Authors:  Nikolaos Scarmeas; Eric Zarahn; Karen E Anderson; John Hilton; Joseph Flynn; Ronald L Van Heertum; Harold A Sackeim; Yaakov Stern
Journal:  Neuroimage       Date:  2003-07       Impact factor: 6.556

4.  Different partial volume correction methods lead to different conclusions: An (18)F-FDG-PET study of aging.

Authors:  Douglas N Greve; David H Salat; Spencer L Bowen; David Izquierdo-Garcia; Aaron P Schultz; Ciprian Catana; J Alex Becker; Claus Svarer; Gitte M Knudsen; Reisa A Sperling; Keith A Johnson
Journal:  Neuroimage       Date:  2016-02-23       Impact factor: 6.556

5.  Optomotor and neuropsychological performance in old age.

Authors:  C Klein; B Fischer; K Hartnegg; W H Heiss; M Roth
Journal:  Exp Brain Res       Date:  2000-11       Impact factor: 1.972

6.  Regional cerebral glucose consumption measured by positron emission tomography in patients with Wilson's disease.

Authors:  T Kuwert; H Hefter; D Scholz; M Milz; P Weiss; G Arendt; H Herzog; M Loken; M Hennerici; L E Feinendegen
Journal:  Eur J Nucl Med       Date:  1992

7.  Normal striatal glucose consumption in two patients with benign hereditary chorea as measured by positron emission tomography.

Authors:  T Kuwert; H W Lange; K J Langen; H Herzog; H Hefter; A Aulich; L E Feinendegen
Journal:  J Neurol       Date:  1990-04       Impact factor: 4.849

8.  Brain FDG PET study of normal aging in Japanese: effect of atrophy correction.

Authors:  Daisuke Yanase; Ichiro Matsunari; Kazuyoshi Yajima; Weiping Chen; Akihiko Fujikawa; Shintaro Nishimura; Hiroshi Matsuda; Masahito Yamada
Journal:  Eur J Nucl Med Mol Imaging       Date:  2005-03-10       Impact factor: 9.236

9.  Age-related changes in brain: II. Positron emission tomography of frontal and temporal lobe glucose metabolism in normal subjects.

Authors:  S De Santi; M J de Leon; A Convit; C Tarshish; H Rusinek; W H Tsui; E Sinaiko; G J Wang; E Bartlet; N Volkow
Journal:  Psychiatr Q       Date:  1995

10.  Effects of sex and normal aging on regional brain activation during verbal memory performance.

Authors:  Erin A Hazlett; William Byne; Adam M Brickman; Effie M Mitsis; Randall Newmark; M Mehmet Haznedar; Danielle T Knatz; Amy D Chen; Monte S Buchsbaum
Journal:  Neurobiol Aging       Date:  2008-11-21       Impact factor: 4.673
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