Literature DB >> 3497165

Brain blood volume, flow, and oxygen utilization measured with 15O radiotracers and positron emission tomography: revised metabolic computations.

T O Videen, J S Perlmutter, P Herscovitch, M E Raichle.   

Abstract

We have revised our methods for calculating regional blood volume, flow, oxygen extraction, and oxygen utilization from positron emission tomography data obtained using 15O-labeled radiotracers. These revisions include radioactive decay explicitly within the model equations instead of requiring all measured activity to be corrected for decay prior to incorporation in the equations. The revised equations yield small but significant differences in the computed values.

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Year:  1987        PMID： 3497165     DOI： 10.1038/jcbfm.1987.97

Source DB:  PubMed          Journal:  J Cereb Blood Flow Metab        ISSN： 0271-678X            Impact factor:   6.200


  35 in total

1.  A default mode of brain function.

Authors:  M E Raichle; A M MacLeod; A Z Snyder; W J Powers; D A Gusnard; G L Shulman
Journal:  Proc Natl Acad Sci U S A       Date:  2001-01-16       Impact factor: 11.205

2.  Autoregulation of cerebral blood flow to changes in arterial pressure in mild Alzheimer's disease.

Authors:  Allyson R Zazulia; Tom O Videen; John C Morris; William J Powers
Journal:  J Cereb Blood Flow Metab       Date:  2010-08-25       Impact factor: 6.200

3.  Measurement of cerebral blood flow with a bolus of oxygen-15-labelled water: comparison of dynamic and integral methods.

Authors:  A Bol; P Vanmelckenbeke; C Michel; M Cogneau; A M Goffinet
Journal:  Eur J Nucl Med       Date:  1990

4.  Platelet mitochondrial complex I and I+III activities do not correlate with cerebral mitochondrial oxidative metabolism.

Authors:  William J Powers; Richard H Haas; Thuy Le; Tom O Videen; Joanne Markham; Joel S Perlmutter
Journal:  J Cereb Blood Flow Metab       Date:  2010-10-20       Impact factor: 6.200

5.  Effect of High-Dose Simvastatin on Cerebral Blood Flow and Static Autoregulation in Subarachnoid Hemorrhage.

Authors:  Michael N Diringer; Rajat Dhar; Michael Scalfani; Allyson R Zazulia; Michael Chicoine; William J Powers; Colin P Derdeyn
Journal:  Neurocrit Care       Date:  2016-08       Impact factor: 3.210

6.  SANGUINATE™ (PEGylated Carboxyhemoglobin Bovine) Improves Cerebral Blood Flow to Vulnerable Brain Regions at Risk of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage.

Authors:  Rajat Dhar; Hemant Misra; Michael N Diringer
Journal:  Neurocrit Care       Date:  2017-12       Impact factor: 3.210

7.  Validation of the reference tissue model for estimation of dopaminergic D2-like receptor binding with [18F](N-methyl)benperidol in humans.

Authors:  Jo Ann V Antenor-Dorsey; Joanne Markham; Stephen M Moerlein; Tom O Videen; Joel S Perlmutter
Journal:  Nucl Med Biol       Date:  2008-04       Impact factor: 2.408

8.  Cerebral hemodynamic and metabolic effects of equi-osmolar doses mannitol and 23.4% saline in patients with edema following large ischemic stroke.

Authors:  Michael N Diringer; Michael T Scalfani; Allyson R Zazulia; Tom O Videen; Raj Dhar
Journal:  Neurocrit Care       Date:  2011-02       Impact factor: 3.210

9.  A possible substrate for dopamine-related changes in mood and behavior: prefrontal and limbic effects of a D3-preferring dopamine agonist.

Authors:  Kevin J Black; Tamara Hershey; Jonathan M Koller; Tom O Videen; Mark A Mintun; Joseph L Price; Joel S Perlmutter
Journal:  Proc Natl Acad Sci U S A       Date:  2002-12-13       Impact factor: 11.205

10.  Metabolic control of resting hemispheric cerebral blood flow is oxidative, not glycolytic.

Authors:  William J Powers; Tom O Videen; Joanne Markham; Vonn Walter; Joel S Perlmutter
Journal:  J Cereb Blood Flow Metab       Date:  2011-02-09       Impact factor: 6.200
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