Literature DB >> 3497116

Effects of adriamycin, 4-hydroperoxycyclophosphamide and ASTA Z 7557 (INN mafosfamide) on the release of IL-2 and IL-1 in vitro.

T A Abdul Hamied, D Parker, J L Turk.   

Abstract

Adriamycin (ADR), 4-hydroperoxycyclophosphamide (4-OOHCYP) and the new cyclophosphamide derivative AZ 7557 (AZ) were tested for their effects on the release of the Interleukins IL-2 and IL-1 from rat spleen cells and peritoneal exudate macrophages respectively. ADR was found to enhance IL-2 release and less effectively IL-1 release. 4-OOHCYP and AZ were found to inhibit IL-2 release but had no effect on IL-1 production. It is suggested that the modulation of IL-2 levels by these drugs is unlikely to be mediated by their effects on IL-1.

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Year:  1987        PMID： 3497116     DOI： 10.1016/0192-0561(87)90061-0

Source DB:  PubMed          Journal:  Int J Immunopharmacol        ISSN： 0192-0561


  10 in total

1.  Enhancement of interleukin-2 release in rats by treatment with bleomycin and adriamycin in vivo.

Authors:  T A Abdul Hamied; J L Turk
Journal:  Cancer Immunol Immunother       Date:  1987       Impact factor: 6.968

2.  Effect of anticancer drugs on the release of interferon gamma in vitro.

Authors:  K Ahmed; P H van der Meide; J L Turk
Journal:  Cancer Immunol Immunother       Date:  1989       Impact factor: 6.968

3.  Potentiation of interleukin-2 release by anti cancer drugs.

Authors:  J L Turk; T A Abdul Hamied; D Parker
Journal:  Agents Actions       Date:  1989-01

4.  Effect of anticancer agents neothramycin, aclacinomycin, FK-565 and FK-156 on the release of interleukin-2 and interleukin-1 in vitro.

Authors:  K Ahmed; J L Turk
Journal:  Cancer Immunol Immunother       Date:  1989       Impact factor: 6.968

Review 5.  Cardiotoxicity of chemotherapeutic agents: incidence, treatment and prevention.

Authors:  V B Pai; M C Nahata
Journal:  Drug Saf       Date:  2000-04       Impact factor: 5.606

6.  Suppression of human monocyte interleukin 1 production by the plant alkaloid tetrandrine.

Authors:  W K Seow; A Ferrante; S Y Li; Y H Thong
Journal:  Clin Exp Immunol       Date:  1989-01       Impact factor: 4.330

7.  CP-115,953 stimulates cytokine production by lymphocytes.

Authors:  K Riesbeck; A Forsgren
Journal:  Antimicrob Agents Chemother       Date:  1995-02       Impact factor: 5.191

8.  Effect of anticancer drugs on the release of tumour necrosis factor in vitro.

Authors:  S I Hasan; K Ahmed; J L Turk
Journal:  Cancer Immunol Immunother       Date:  1990       Impact factor: 6.968

9.  Fatal exacerbation of paraneoplastic systemic sclerosis after neoadjuvant chemotherapy in a breast cancer patient.

Authors:  Ruby Kochhar; Jay N Umbreit
Journal:  Clin Rheumatol       Date:  2004-04-14       Impact factor: 2.980

10.  Acute left ventricular insufficiency in a Burkitt Lymphoma patient with myocardial involvement and extensive local tumor cell lysis: a case report.

Authors:  Maren Schmiester; Eva Tranter; Alessandro Lorusso; Florian Blaschke; Dominik Geisel; Lars Bullinger; Frederik Damm; Il-Kang Na
Journal:  BMC Cardiovasc Disord       Date:  2022-02-04       Impact factor: 2.298
  10 in total

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