| Literature DB >> 34961559 |
Saija Ahonen1, Ian Seath2, Clare Rusbridge3,4, Susan Holt2, Gill Key2, Travis Wang1, Peixiang Wang1, Berge A Minassian5,6.
Abstract
Entities:
Year: 2021 PMID: 34961559 PMCID: PMC8711151 DOI: 10.1186/s40575-021-00104-3
Source DB: PubMed Journal: Canine Med Genet ISSN: 2662-9380
Fig. 1Genotyping is performed using Southern blot. Southern blot is used for genotyping as PCR based methods cannot reliably distinguish the different genotypes due to the type of the mutation. The affected dogs (a) are homozygous for the dodecamer repeat expansion mutation with multiple dodecamer repeats, carrier (c) dogs have the normal and mutated allele and clear dogs (WT) have three copies of the repeat [8]