Literature DB >> 34956486

Study on biomechanical analysis of two-level cervical Mobi-C and arthrodesis.

Chao Sun1, Yang Li1, Rongjie Feng1, Shijie Han1.   

Abstract

OBJECTIVE: To investigate the range of motion (ROM) index of a two-level cervical arthroplasty.
METHODS: Seven human cadaveric spines were biomechanically examined from C2 level to T1 level under intact status and the following conditions: 2-level arthroplasty (C4-C6) employing Mobi-C devices (MM group), 2-level anterior cervical discectomy and fusions (2-ACDFs) (FF group), and both as a hybrid surgery (HS) (MF group and FM group). Multidirectional flexibility examination was conducted according to the Panjabi hybrid testing protocol. Unconstrained intact moments of ±1.5 NM were performed for axial rotation (AR) flexion/extension (FE), and lateral bending (LB).
RESULTS: No statistical differences were found between the intact spine and MM group at the operative- and adjacent-level kinematics in the three loading conditions, except that C4-C5 ROM significantly increased in the axial rotation loading (P<0.05). Compared with the intact spine, MF group led to a significant decrease at the arthrodesis segment ROM C5-C6 in the three loading (P<0.05), with corresponding significantly increased at C4-C5 in FE and AR (P<0.05). FM group resulted in a significant decrease in ROM C4-C5 (P<0.05) with corresponding significantly increased at C5-C6 in FE, AR and LB (P<0.05). There was not any difference for non-operative level kinematics between MF group and FM group and intact spine. Compared with the intact spine, FF group led to a significant decrease at the arthrodesis-levels (P<0.05) and marked increase at the non-operative level kinematics.
CONCLUSION: A two-level Mobi-C and Hybrid construct generated better biomechanical conditions. This study suggested that two-level cervical total disc replacement or HS could become an alternative approach for therapy of two-level consecutive cervical spondylosis. AJTR
Copyright © 2021.

Entities:  

Keywords:  Biomechanics; Mobi-C; ROM; cervical disc arthroplasty; two-level

Year:  2021        PMID: 34956486      PMCID: PMC8661242     

Source DB:  PubMed          Journal:  Am J Transl Res        ISSN: 1943-8141            Impact factor:   4.060


  43 in total

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4.  Comparative efficacy and acceptability of antidepressants, psychotherapies, and their combination for acute treatment of children and adolescents with depressive disorder: a systematic review and network meta-analysis.

Authors:  Xinyu Zhou; Teng Teng; Yuqing Zhang; Cinzia Del Giovane; Toshi A Furukawa; John R Weisz; Xuemei Li; Pim Cuijpers; David Coghill; Yajie Xiang; Sarah E Hetrick; Stefan Leucht; Mengchang Qin; Jürgen Barth; Arun V Ravindran; Lining Yang; John Curry; Li Fan; Susan G Silva; Andrea Cipriani; Peng Xie
Journal:  Lancet Psychiatry       Date:  2020-07       Impact factor: 27.083

5.  The range and nature of flexion-extension motion in the cervical spine.

Authors:  A Holmes; C Wang; Z H Han; G T Dang
Journal:  Spine (Phila Pa 1976)       Date:  1994-11-15       Impact factor: 3.468

6.  Two-level total disc replacement with Mobi-C cervical artificial disc versus anterior discectomy and fusion: a prospective, randomized, controlled multicenter clinical trial with 4-year follow-up results.

Authors:  Reginald J Davis; Pierce Dalton Nunley; Kee D Kim; Michael S Hisey; Robert J Jackson; Hyun W Bae; Gregory A Hoffman; Steven E Gaede; Guy O Danielson; Charles Gordon; Marcus B Stone
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7.  Cervical disc replacement in patients with and without previous adjacent level fusion surgery: a prospective study.

Authors:  Frank M Phillips; Todd R Allen; John J Regan; Todd J Albert; Andrew Cappuccino; John G Devine; Jeanette E Ahrens; John A Hipp; Paul C McAfee
Journal:  Spine (Phila Pa 1976)       Date:  2009-03-15       Impact factor: 3.468

8.  Long-term kinematic analysis of cervical spine after single-level implantation of Bryan cervical disc prosthesis.

Authors:  Won Hyung A Ryu; Izabela Kowalczyk; Neil Duggal
Journal:  Spine J       Date:  2013-04-09       Impact factor: 4.166

9.  Multi-center, prospective, randomized, controlled investigational device exemption clinical trial comparing Mobi-C Cervical Artificial Disc to anterior discectomy and fusion in the treatment of symptomatic degenerative disc disease in the cervical spine.

Authors:  Michael S Hisey; Hyun W Bae; Reginald Davis; Steven Gaede; Greg Hoffman; Kee Kim; Pierce D Nunley; Daniel Peterson; Ralph Rashbaum; John Stokes
Journal:  Int J Spine Surg       Date:  2014-12-01

10.  Clinical and radiological outcomes of dynamic cervical implant arthroplasty: A 5-year follow-up.

Authors:  Li Zou; Xin Rong; Xi-Jiao Liu; Hao Liu
Journal:  World J Clin Cases       Date:  2021-06-06       Impact factor: 1.337

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