Billy Lin1, Brian D Jaros2, Eugene A Grossi2,3,4, Muhamed Saric2,3,5, Michael S Garshick6,2,5, Robert Donnino6,2,3,5. 1. Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California. 2. NYU School of Medicine, NYU Langone Health, New York City, New York. 3. Veterans Affairs Medical Center, New York (Manhattan Campus), New York City, New York. 4. Division of Cardiac Surgery, Department of Cardiothoracic Surgery, NYU Langone Health, New York City, New York. 5. Leon H. Charney Division of Cardiology, NYU Langone Health, New York City, New York. 6. Authors share senior authorship.
Abstract
OBJECTIVES: In patients with atrial fibrillation, incomplete left atrial appendage (LAA) closure is associated with an increased risk for cardio-embolic events compared to complete closure. In this study, we aimed to determine the prevalence and risk factors for incomplete surgical closure of the LAA in the modern surgical era. METHODS: Records of 74 patients with surgical LAA closure who underwent follow-up transesophageal echocardiogram for any reason between 2010 and 2016, were assessed for incomplete closure. Complete closure was defined by absence of Doppler or color flow between the left atrial appendage and the left atrial body in more than 2 orthogonal views. RESULTS: Surgical LAA closure was incomplete in 21 patients (28%) and complete in 53 patients (72%). All included cases were completed via oversewing method with a double layer of running suture with or without excision of the LAA. While no individual demographic, echocardiographic, or surgical feature was significantly different between groups, incomplete closure of the LAA was more prevalent in patients with two or more of the risk factors; female sex, hypertension, and hyperlipidemia (OR 5.1, 95%Cl 1.5-17). CONCLUSIONS: A significant rate of incomplete surgical LAA closure still exists in the modern surgical era, and the presence of multiple risk factors associate an increased risk of incomplete closure.
OBJECTIVES: In patients with atrial fibrillation, incomplete left atrial appendage (LAA) closure is associated with an increased risk for cardio-embolic events compared to complete closure. In this study, we aimed to determine the prevalence and risk factors for incomplete surgical closure of the LAA in the modern surgical era. METHODS: Records of 74 patients with surgical LAA closure who underwent follow-up transesophageal echocardiogram for any reason between 2010 and 2016, were assessed for incomplete closure. Complete closure was defined by absence of Doppler or color flow between the left atrial appendage and the left atrial body in more than 2 orthogonal views. RESULTS: Surgical LAA closure was incomplete in 21 patients (28%) and complete in 53 patients (72%). All included cases were completed via oversewing method with a double layer of running suture with or without excision of the LAA. While no individual demographic, echocardiographic, or surgical feature was significantly different between groups, incomplete closure of the LAA was more prevalent in patients with two or more of the risk factors; female sex, hypertension, and hyperlipidemia (OR 5.1, 95%Cl 1.5-17). CONCLUSIONS: A significant rate of incomplete surgical LAA closure still exists in the modern surgical era, and the presence of multiple risk factors associate an increased risk of incomplete closure.
Entities:
Keywords:
Atrial fibrillation; Cardiac surgery; Left atrial appendage; Left atrial appendage thrombus; Left atrium; TEE; Transesophageal echocardiography
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