| Literature DB >> 34938930 |
Yusuf Jameel1, M Rajib Hassan Mozumder2,3, Alexander van Geen2, Charles F Harvey1.
Abstract
Well-switching programs in Bangladesh have successfully lowered arsenic exposure. In these programs, households switch from wells that are labeled "unsafe" to nearby wells labeled "safe," but these designations are usually based on inherently inaccurate field kit measurements. Here, we (a) compare the efficacy of field-kit measurements to accurate laboratory measurements for well switching, (b) investigate the potential impact on well switching of the chosen "safe" threshold, and (c) consider the possible benefits of providing more detailed concentration information than just "safe" and "unsafe." We explore different hypothetical mitigation scenarios by combining two extensive data sets from Araihazar Bangladesh: a blanket survey of 6595 wells over 25 km2 based on laboratory measurements and 943 paired kit and laboratory measurements from the same area. The results indicate that the decline in average arsenic exposure from relying on kit rather than laboratory data is modest in relation to the logistical and financial challenge of delivering exclusively laboratory data. The analysis further indicates that the 50 μg/L threshold used in Bangladesh to distinguish safe and unsafe wells, rather than the WHO guideline of 10 μg/L, is close to optimal in terms of average exposure reduction. We also show that providing kit data at the maximum possible resolution rather than merely classifying wells as unsafe or safe would be even better. These findings are relevant as the government of Bangladesh is about to launch a new blanket testing campaign of millions of wells using field kits.Entities:
Keywords: Bangladesh; arsenic; field kit; public health; well‐switching
Year: 2021 PMID: 34938930 PMCID: PMC8670558 DOI: 10.1029/2021GH000464
Source DB: PubMed Journal: Geohealth ISSN: 2471-1403
Figure 1Schematic of a hypothetical group of wells and their arsenic concentrations that illustrates well switching patterns. Top panel: Positions and arsenic concentrations for eight hypothetical wells (shown in gray circle) and the 100‐m radii in which switching is possible. First column: Examples where arsenic concentrations are autocorrelated in space, generally decreasing to the east. Second column: Examples where arsenic concentrations are uncorrelated in space. Row A: The ideal base case where switches are based on accurate continuous arsenic measurements. Rows B and C: Switches are based on thresholds. Row D: Switches are based on kit measurements that mis‐assign some wells to the wrong category. In row D, incorrectly categoriezed wells due to field‐kit errors are shown in star.
Figure 2Distribution of spectrometric arsenic concentrations (y‐axis) within kit categories (x‐axis) for the 943 wells with paired spectrometric and kit measurements. Kit categories shown in blue, and green are classified as uncontaminated and kit categories shown in red are classified as contaminated. The 10 and 50 μg/L threshold are shown in blue and green lines. The data clearly show that the true arsenic range for any nominal category exceeds the range allotted to it.
Figure 3Distribution of laboratory measured arsenic concentration: (a) 943 wells with paired laboratory and kit measurements and (b) 6595 wells surveyed in 2000–2001.
Figure 4Frequency distribution (orange bars) of the arsenic concentration (x‐axis) for the respective nominal kit categories for the paired data set with 943 measurements. The red line is the best fit parametric distribution to the data for each kit categories. The placards posted on well based on the kit categories are also shown in each panel. Wells with blue and green placards are considered as uncontaminated and wells with red placards are considered as contaminated.
Density and Conditional Probabilities of the Nominal Kit Categories for the Laboratory (Spectrometric Measured) Concentration of 100 μg/L
| Nominal kit categories | Density | Conditional probabilities |
|---|---|---|
| Kit category 1 (nominal range 0–1 μg/L) | <0.0001 |
|
| Kit category 2 (nominal range 1–10 μg/L) | <0.0001 |
|
| Kit category 3 (nominal range 10–20 μg/L) | <0.0001 |
|
| Kit category 4 (nominal range 20–50 μg/L) | <0.0001 |
|
| Kit category 5 (nominal range 50–100 μg/L) | 0.005 |
|
| Kit category 6 (nominal range 100–200 μg/L) | 0.008 |
|
| Kit category 7 (nominal range 200–300 μg/L) | 0.003 |
|
| Kit category 8 (nominal range 300–500 μg/L) | 0.0003 |
|
| Kit category 9 (nominal range 500–1000 μg/L) | <0.0001 |
|
Note. Kit categories (5–7) with high probability are highlighted in bold. The conditional probabilities are calculated using Equation 1.
Possible Switching Scenarios Based on the Probability of Correct, and Incorrect Nominal Kit Category Assignments
| Type of switching | Probability of switching | Description |
|---|---|---|
| Ideal Switching |
| Switched from correctly identified unsafe well to correctly identified safe well |
| Bad Switching |
| Switched from correctly identified unsafe well to incorrectly identified safe well |
| Very bad switching |
| Switched from incorrectly identified safe well to incorrectly identified unsafe well |
| Unnecessary switching |
| Switched from incorrectly identified safe well to correctly identified safe well |
| Missed switching |
| False negative identification of unsafe wells. Therefore, no switching |
Note. i is the different kit category and θ is the true arsenic concentration. Actual switching only takes place when the well to be switched to lies in a 100‐m radius of the well that is being switched from.
Figure 5(a) Arsenic concentration of 6595 Araihazar wells measured by spectrometric method. (b) Correct (white circle with black border), and incorrect assignments (purple and brown circles) for simulated categorization based on kit measurements (see Table 2). Wells with As ≤ 10 μg/L that are labeled as green or red and wells with 10 < As ≤ 50 μg/L that are labeled as red are shown in purple. Wells with 10 < As ≤ 50 μg/L that are labeled as blue and wells with As > 50 labeled as blue and green are shown in brown. Two regions with large proportion of correct assignments are highlighted in black ellipses. Inset: Map of Bangladesh. Araihazar is 30 km east of Dhaka (pink star).
Figure 6(a) Probability of assigning the different color placards (blue, green and red) from kit measurements of arsenic as a function of arsenic concentration. (b) Probability of assigning incorrect color placard as a function of arsenic concentration. For wells with As ≤ 10 μg/L, probability of incorrect assignment is defined as the sum of assigning green and red placards. For well with 10 < As ≤ 50 μg/L, probability of incorrect assignment is defined as the sum of assigning blue and red placards. For wells with As > 50 μg/L, probability of incorrect assignment is defined as the sum of assigning blue and green placards. (c) Probability of assigning a well as safe (light blue) and unsafe (black) as a function of arsenic concentration.
Summary Statistics of Exposure Post Switching and Percentage of Consumers Experiencing Change in Arsenic Exposure for the Different Switching Scenarios
Note. Before switching the exposure is the average arsenic concentration across wells 134 μg/L. Scenarios B2 and B4 have same values for the different rows as the optimal threshold (B4) for switching between uncontaminated and contaminated (red and green) wells is observed when wells with kit categories 1–4 are labeled green and categories 5–9 are labeled red which is same as scenario B2.
Figure 7(a) Mean exposure post switching for different “safe” thresholds. The minimum exposure is at 41 μg/L. (b) Mean exposure post switching based on categorical kit measurements. The minimum exposure post switching is observed if wells with categories 1–4 are labeled green and wells with categories 5–9 are labeled red.