| Literature DB >> 34936666 |
Catherine Gimbrone1, Caroline Rutherford1, Sasikiran Kandula2, Gonzalo Martínez-Alés1, Jeffrey Shaman2, Mark Olfson1,3, Madelyn S Gould1,3, Sen Pei2, Marta Galanti2, Katherine M Keyes1.
Abstract
During the COVID-19 pandemic, US populations have experienced elevated rates of financial and psychological distress that could lead to increases in suicide rates. Rapid ongoing mental health monitoring is critical for early intervention, especially in regions most affected by the pandemic, yet traditional surveillance data are available only after long lags. Novel information on real-time population isolation and concerns stemming from the pandemic's social and economic impacts, via cellular mobility tracking and online search data, are potentially important interim surveillance resources. Using these measures, we employed transfer function model time-series analyses to estimate associations between daily mobility indicators (proportion of cellular devices completely at home and time spent at home) and Google Health Trends search volumes for terms pertaining to economic stress, mental health, and suicide during 2020 and 2021 both nationally and in New York City. During the first pandemic wave in early-spring 2020, over 50% of devices remained completely at home and searches for economic stressors exceeded 60,000 per 10 million. We found large concurrent associations across analyses between declining mobility and increasing searches for economic stressor terms (national proportion of devices at home: cross-correlation coefficient (CC) = 0.6 (p-value <0.001)). Nationally, we also found strong associations between declining mobility and increasing mental health and suicide-related searches (time at home: mood/anxiety CC = 0.53 (<0.001), social stressor CC = 0.51 (<0.001), suicide seeking CC = 0.37 (0.006)). Our findings suggest that pandemic-related isolation coincided with acute economic distress and may be a risk factor for poor mental health and suicidal behavior. These emergent relationships warrant ongoing attention and causal assessment given the potential for long-term psychological impact and suicide death. As US populations continue to face stress, Google search data can be used to identify possible warning signs from real-time changes in distributions of population thought patterns.Entities:
Mesh:
Year: 2021 PMID: 34936666 PMCID: PMC8694413 DOI: 10.1371/journal.pone.0260931
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Fig 1Mobility indicators over time nationally and in the NYC DMA: 2020–2021.
Note: Mobility data was aggregated to the weekly-level for time-series analyses.
Fig 2Google Health Trends search volumes for economic stressor terms over time nationally and in the NYC DMA: 2020–2021.
Fig 3Google Health Trends search volumes for suicide seeking, mood and anxiety, and social stressor terms over time nationally and in the NYC DMA: 2020–2021.
Fig 4Heatmaps of cross-correlation coefficients for mobility indicators and Google Health Trends search volumes for economic stressor terms nationally and in the NYC DMA: 2020–2021.
P-values listed within cells. Note on interpretation: A cross-correlation coefficient at a negative weekly lag indicates that changes in the explanatory time series lead changes in the dependent time series that number of weeks later. A cross-correlation coefficient at a positive weekly lag indicates that changes in the dependent time series lead changes in the explanatory time series that number of weeks later. Correlations at the 0-week lag suggest that changes in both time series were concurrent. A positive cross-correlation coefficient indicates that there is a direct correlation between the time series and a negative cross-correlation coefficient indicates that there is an inverse correlation between the time series.
Fig 5Heatmaps of cross-correlation coefficients for mobility indicators and Google Health Trends search volumes for suicide seeking, mood and anxiety, and social stressor terms nationally and in the NYC DMA: 2020–2021.
P-values listed within cells. Note on interpretation: A cross-correlation coefficient at a negative weekly lag indicates that changes in the explanatory time series lead changes in the dependent time series that number of weeks later. A cross-correlation coefficient at a positive weekly lag indicates that changes in the dependent time series lead changes in the explanatory time series that number of weeks later. Correlations at the 0-week lag suggest that changes in both time series were concurrent. A positive cross-correlation coefficient indicates that there is a direct correlation between the time series and a negative cross-correlation coefficient indicates that there is an inverse correlation between the time series.