Literature DB >> 3492803

Clinical and laboratory characteristics of patients with speckled pattern antinuclear antibodies.

S A McMillan, A C Fay, A J Taggart, J D McCrea, S D Roberts, M W Boyd, J K Nelson, M Haire.   

Abstract

Fifty patients whose sera contained a speckled antinuclear antibody (ANA) were interviewed and examined to determine if there was any relationship between their clinical manifestations and the presence of certain serological markers. The results suggest that speckled ANA is usually found in patients with definite connective tissue diseases, but a significant minority have incomplete or early stages of these diseases. Characterisation of the antibody to extractable nuclear antigen (ENA) and other serological markers does not normally assist in making a clinical diagnosis, but the detection of a speckled ANA should prompt further investigation and careful follow-up.

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Year:  1986        PMID： 3492803      PMCID： PMC2448365     

Source DB:  PubMed          Journal:  Ulster Med J        ISSN： 0041-6193


  15 in total

1.  Identification of antibodies to nuclear acidic antigens by counterimmunoelectrophoresis.

Authors:  N Kurata; E M Tan
Journal:  Arthritis Rheum       Date:  1976 May-Jun

2.  Precipitating antibody to D.N.A. detected by two-stage electroimmunodiffusion. Study in S.L.E. and in rheumatoid arthritis.

Authors:  G D Johnson; J P Edmonds; E J Holborow
Journal:  Lancet       Date:  1973-10-20       Impact factor: 79.321

3.  Studies on antibodies to histones by immunofluorescence.

Authors:  E M Tan; J Robinson; P Robitaille
Journal:  Scand J Immunol       Date:  1976       Impact factor: 3.487

4.  Mixed connective tissue disease: a subsequent evaluation of the original 25 patients.

Authors:  S H Nimelstein; S Brody; D McShane; H R Holman
Journal:  Medicine (Baltimore)       Date:  1980-07       Impact factor: 1.889

5.  Purification of an acidic nuclear protein antigen and demonstration of its antibodies in subsets of patients with sicca syndrome.

Authors:  M Akizuki; M J Boehm-Truitt; S S Kassan; A D Steinberg; T M Chused
Journal:  J Immunol       Date:  1977-09       Impact factor: 5.422

6.  Association of antinuclear and antinucleolar antibodies in progressive systemic sclerosis.

Authors:  R M Bernstein; J C Steigerwald; E M Tan
Journal:  Clin Exp Immunol       Date:  1982-04       Impact factor: 4.330

7.  Preliminary criteria for the classification of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee.

Authors: 
Journal:  Arthritis Rheum       Date:  1980-05

8.  Ro(SSA) and La(SSB) antibodies in the clinical spectrum of Sjögren's syndrome.

Authors:  E L Alexander; T J Hirsch; F C Arnett; T T Provost; M B Stevens
Journal:  J Rheumatol       Date:  1982 Mar-Apr       Impact factor: 4.666

9.  Clinical and laboratory associations of anticentromere antibody in patients with progressive systemic sclerosis.

Authors:  V D Steen; G L Ziegler; G P Rodnan; T A Medsger
Journal:  Arthritis Rheum       Date:  1984-02

10.  Anti-SS-A antibody and other antinuclear antibodies in systemic lupus erythematosus.

Authors:  E Scopelitis; J J Biundo; M A Alspaugh
Journal:  Arthritis Rheum       Date:  1980-03
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