| Literature DB >> 34918252 |
Jieru Yang1, Armira Azuar1, Istvan Toth2,3,4, Mariusz Skwarczynski5.
Abstract
Liposomes, which are artificial phospholipid vesicles with a bilayer membrane structure, have been developed and evaluated as a promising delivery system for vaccines. Here, we describe a procedure for the encapsulation of lipopeptide vaccines into liposomes. A liposomal formulation of lipid-core peptide was prepared via thin-film hydration followed by extrusion. The physicochemical properties of the liposomes, including their size, polydispersity, surface charge, and morphology, were analyzed using dynamic light scattering and transmission electron microscopy.Entities:
Keywords: Extrusion; Lipopeptides; Liposomes; Vaccine delivery
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Year: 2022 PMID: 34918252 DOI: 10.1007/978-1-0716-1892-9_15
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745