Literature DB >> 34918252

Liposomes for the Delivery of Lipopeptide Vaccines.

Jieru Yang1, Armira Azuar1, Istvan Toth2,3,4, Mariusz Skwarczynski5.   

Abstract

Liposomes, which are artificial phospholipid vesicles with a bilayer membrane structure, have been developed and evaluated as a promising delivery system for vaccines. Here, we describe a procedure for the encapsulation of lipopeptide vaccines into liposomes. A liposomal formulation of lipid-core peptide was prepared via thin-film hydration followed by extrusion. The physicochemical properties of the liposomes, including their size, polydispersity, surface charge, and morphology, were analyzed using dynamic light scattering and transmission electron microscopy.
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Extrusion; Lipopeptides; Liposomes; Vaccine delivery

Mesh:

Substances:

Year:  2022        PMID: 34918252     DOI: 10.1007/978-1-0716-1892-9_15

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  15 in total

Review 1.  Lipopeptide vaccines--yesterday, today, and tomorrow.

Authors:  Lbachir BenMohamed; Steven L Wechsler; Anthony B Nesburn
Journal:  Lancet Infect Dis       Date:  2002-07       Impact factor: 25.071

Review 2.  Liposome-based delivery system for vaccine candidates: constructing an effective formulation.

Authors:  Ashwini Kumar Giddam; Ashwin Kumar Giddam; Mehfuz Zaman; Mariusz Skwarczynski; Istvan Toth
Journal:  Nanomedicine (Lond)       Date:  2012-12       Impact factor: 5.307

3.  Cholic Acid-based Delivery System for Vaccine Candidates against Group A Streptococcus.

Authors:  Armira Azuar; Lili Zhao; Tsui Ting Hei; Reshma J Nevagi; Stacey Bartlett; Waleed M Hussein; Zeinab G Khalil; Robert J Capon; Istvan Toth; Mariusz Skwarczynski
Journal:  ACS Med Chem Lett       Date:  2019-07-24       Impact factor: 4.345

4.  Multilayer engineered nanoliposomes as a novel tool for oral delivery of lipopeptide-based vaccines against group A Streptococcus.

Authors:  Nirmal Marasini; Ashwini K Giddam; Khairunnisa A Ghaffar; Michael R Batzloff; Michael F Good; Mariusz Skwarczynski; Istvan Toth
Journal:  Nanomedicine (Lond)       Date:  2016-04-14       Impact factor: 5.307

5.  Structure-activity relationship of group A streptococcus lipopeptide vaccine candidates in trimethyl chitosan-based self-adjuvanting delivery system.

Authors:  Reshma J Nevagi; Wei Dai; Zeinab G Khalil; Waleed M Hussein; Robert J Capon; Mariusz Skwarczynski; Istvan Toth
Journal:  Eur J Med Chem       Date:  2019-06-18       Impact factor: 6.514

6.  Lipid core peptide targeting the cathepsin D hemoglobinase of Schistosoma mansoni as a component of a schistosomiasis vaccine.

Authors:  Annette M Dougall; Mariusz Skwarczynski; Makan Khoshnejad; Saranya Chandrudu; Norelle L Daly; Istvan Toth; Alex Loukas
Journal:  Hum Vaccin Immunother       Date:  2013-11-14       Impact factor: 3.452

Review 7.  Status and future prospects of lipid-based particulate delivery systems as vaccine adjuvants and their combination with immunostimulators.

Authors:  Pernille Nordly; Henriette Baun Madsen; Hanne Moerck Nielsen; Camilla Foged
Journal:  Expert Opin Drug Deliv       Date:  2009-07       Impact factor: 6.648

8.  Lipopeptide Nanoparticles: Development of Vaccines against Hookworm Parasite.

Authors:  Abdullah A H Ahmad Fuaad; Mark S Pearson; Darren A Pickering; Luke Becker; Guangzu Zhao; Alex C Loukas; Mariusz Skwarczynski; Istvan Toth
Journal:  ChemMedChem       Date:  2015-08-12       Impact factor: 3.466

Review 9.  Lipids as Activators of Innate Immunity in Peptide Vaccine Delivery.

Authors:  Stacey Bartlett; Mariusz Skwarczynski; Istvan Toth
Journal:  Curr Med Chem       Date:  2020       Impact factor: 4.530

10.  Lipopeptide-Based Oral Vaccine Against Hookworm Infection.

Authors:  Stacey Bartlett; Ramon M Eichenberger; Reshma J Nevagi; Khairunnisa Abdul Ghaffar; Nirmal Marasini; Yang Dai; Alex Loukas; Istvan Toth; Mariusz Skwarczynski
Journal:  J Infect Dis       Date:  2020-03-02       Impact factor: 5.226

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  1 in total

Review 1.  Naturally-Sourced Antibacterial Polymeric Nanomaterials with Special Reference to Modified Polymer Variants.

Authors:  Marian Rofeal; Fady Abdelmalek; Alexander Steinbüchel
Journal:  Int J Mol Sci       Date:  2022-04-07       Impact factor: 6.208

  1 in total

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