Literature DB >> 3491571

Prospective study of a planned approach to the surgical management of bleeding oesophageal varices.

A A Connacher, F C Campbell, I A Bouchier, A Cuschieri.   

Abstract

A policy of joint management of patients with acute variceal bleeding was constructed and applied prospectively to 37 consecutive patients. According to the protocol, every patient underwent an initial joint assessment by a physician and a surgeon soon after admission and resuscitation, which included age, previous history, physical examination and biochemical profile. Pugh's modification of Child's scoring system was used to assess the severity of the underlying hepatic disorder. Patients in groups A and B who were less than 70 years of age were treated by shunt surgery carried out during the same admission. Patients outwith this category were managed conservatively and a blood transfusion limit (10 units) imposed unless the clinical picture subsequently improved or the liver function was good but the patient was not eligible for surgery because of age. Twenty seven patients underwent shunt surgery, the most frequent procedure being a Warren shunt (n = 21). The average hospital stay in the surgically treated group was 18 days. The 30 day operative mortality was 15%. Two further deaths in the shunted group occurred during the follow-up period (mean = 30 months, range = 6-97 months). Seventeen patients in the shunted group remain well but three have required further therapy because of rebleeding episodes (two with sclerotherapy, one by surgery). Two patients who went abroad after recovery from their shunt surgery have been lost to follow up. The survival in the conservatively treated group was short and recurrent bleeding common. This experience indicates that an initial joint assessment using established criteria reliably identifies the poor prognosis group of patients with variceal haemorrhage and allows the rationalisation of the hospital resources.Early and expeditious selective shunt surgery in the good risk category carries an acceptable mortality and is cost effective in the long term.

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Year:  1986        PMID: 3491571      PMCID: PMC2498334     

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  19 in total

1.  Treatment of bleeding varices by oesophageal transection with the SPTU gun.

Authors:  G W Johnston
Journal:  Ann R Coll Surg Engl       Date:  1977-09       Impact factor: 1.891

2.  Prospective comparative clinical trial with distal splenorenal and mesocaval shunts.

Authors:  F A Reichle; W F Fahmy; M Golsorkhi
Journal:  Am J Surg       Date:  1979-01       Impact factor: 2.565

3.  Selective distal splenorenal shunt. Technique and results of operation.

Authors:  W D Warren; A A Salam; D Hutson; R Zeppa
Journal:  Arch Surg       Date:  1974-03

4.  A review of 15 years' experience in the use of sclerotherapy in the control of acute haemorrhage from oesophageal varices.

Authors:  G W Johnston; H W Rodgers
Journal:  Br J Surg       Date:  1973-10       Impact factor: 6.939

5.  A controlled study of the therapeutic portacaval shunt.

Authors:  R H Resnick; F L Iber; A M Ishihara; T C Chalmers; H Zimmerman
Journal:  Gastroenterology       Date:  1974-11       Impact factor: 22.682

6.  A clinical investigation of the portacaval shunt. V. Survival analysis of the therapeutic operation.

Authors:  F C Jackson; E B Perrin; W R Felix; A G Smith
Journal:  Ann Surg       Date:  1971-10       Impact factor: 12.969

7.  A randomized, controlled trial of the distal splenorenal shunt.

Authors:  L F Rikkers; D Rudman; J T Galambos; J T Fulenwider; W J Millikan; M Kutner; R B Smith; A A Salam; P J Sones; W D Warren
Journal:  Ann Surg       Date:  1978-09       Impact factor: 12.969

8.  Long-term sclerotherapy of bleeding esophageal varices in patients with liver cirrhosis. An evaluation of mortality and rebleeding risk factors.

Authors:  T Sauerbruch; M Weinzierl; W Köpcke; G Paumgartner
Journal:  Scand J Gastroenterol       Date:  1985-01       Impact factor: 2.423

9.  Results of a 12-year randomized trial of portacaval shunt in patients with alcoholic liver disease and bleeding varices.

Authors:  T B Reynolds; A J Donovan; W P Mikkelsen; A G Redeker; F L Turrill; J M Weiner
Journal:  Gastroenterology       Date:  1981-05       Impact factor: 22.682

10.  Distal splenorenal shunt vs. portal-systemic shunt: current status of a controlled trial.

Authors:  H O Conn; R H Resnick; N D Grace; C E Atterbury; D Horst; R J Groszmann; P Gazmuri; R J Gusberg; B Thayer; D Berk; S C Wright; R Vollman; D M Tilson; W V McDermott; J A Cohen; M Kerstein; A L Toole; J P Maselli; S Razvi; A Ishihara; H Stern; C Trey; E T O'Hara; W Widrich; H Aisenberg; H C Stansel; M Zinny
Journal:  Hepatology       Date:  1981 Mar-Apr       Impact factor: 17.425

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