Literature DB >> 3491220

Orbital histoplasmosis due to Histoplasma capsulatum var. duboisii: successful treatment with Septrin.

B G Ajayi, B Osuntokun, O Olurin, O O Kale, T A Junaid.   

Abstract

Four children with orbital histoplasmosis caused by Histoplasma capsulatum var. duboisii (one of whom had been unsuccessfully treated with amphotericin-B) were treated with a combination of trimethoprim and sulphamethoxazole (Septrin) and surgical drainage. All patients improved markedly during therapy with resolution of the lesions, and with no recurrence of infection in three patients, 1 year later. The fourth patient was lost to follow-up. Treatment was devoid of side effects. These findings clearly indicate that Septrin could be a safe alternative to amphotericin-B for the treatment of African histoplasmosis, especially in patients presenting with solitary or localized lesions.

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Year:  1986        PMID： 3491220

Source DB:  PubMed          Journal:  J Trop Med Hyg        ISSN： 0022-5304


  8 in total

1.  Feline histoplasmosis in Brazil: clinical and laboratory aspects and a comparative approach of published reports.

Authors:  Raimunda Sâmia Nogueira Brilhante; Camila Gomes Virginio Coelho; José Júlio Costa Sidrim; Rita Amanda Chaves de Lima; Joyce Fonteles Ribeiro; Rossana Aguiar de Cordeiro; Débora de Souza Collares Maia Castelo-Branco; José Maurício Fonteles Gomes; Lucilene Simões-Mattos; Marcos Renato Franzosi Mattos; Hugo Enrique Orsini Beserra; George Cândido Nogueira; Adriana de Queiroz Pinheiro; Marcos Fábio Gadelha Rocha
Journal:  Mycopathologia       Date:  2011-10-18       Impact factor: 2.574

2.  In vitro effect of sulfamethoxazole-trimethoprim against Histoplasma capsulatum var. capsulatum.

Authors:  Raimunda Sâmia Nogueira Brilhante; Maria Auxiliadora Bezerra Fechine; Rossana de Aguiar Cordeiro; Marcos Fábio Gadelha Rocha; Joyce Fonteles Ribeiro; André Jalles Monteiro; Rita Amanda Chaves de Lima; Jacó Ricarte Lima Mesquita; Zoilo Pires de Camargo; José Júlio Costa Sidrim
Journal:  Antimicrob Agents Chemother       Date:  2010-06-21       Impact factor: 5.191

3.  Gingival histoplasmosis: An atypical presentation of African histoplasmosis in three baboons (Papio spp).

Authors:  Taylor A Johannigman; Olga Gonzalez; John W Dutton; Shyamesh Kumar; Edward J Dick
Journal:  J Med Primatol       Date:  2019-10-08       Impact factor: 0.667

4.  Fusarium and Candida albicans biofilms on soft contact lenses: model development, influence of lens type, and susceptibility to lens care solutions.

Authors:  Yoshifumi Imamura; Jyotsna Chandra; Pranab K Mukherjee; Ali Abdul Lattif; Loretta B Szczotka-Flynn; Eric Pearlman; Jonathan H Lass; Kerry O'Donnell; Mahmoud A Ghannoum
Journal:  Antimicrob Agents Chemother       Date:  2007-11-12       Impact factor: 5.191

Review 5.  Current perspectives on ophthalmic mycoses.

Authors:  Philip A Thomas
Journal:  Clin Microbiol Rev       Date:  2003-10       Impact factor: 26.132

Review 6.  Fungal infections of the orbit.

Authors:  Bipasha Mukherjee; Nirav Dilip Raichura; Md Shahid Alam
Journal:  Indian J Ophthalmol       Date:  2016-05       Impact factor: 1.848

Review 7.  Trimethoprim and other nonclassical antifolates an excellent template for searching modifications of dihydrofolate reductase enzyme inhibitors.

Authors:  Agnieszka Wróbel; Karolina Arciszewska; Dawid Maliszewski; Danuta Drozdowska
Journal:  J Antibiot (Tokyo)       Date:  2019-10-02       Impact factor: 2.649

Review 8.  Histoplasmosis in Children; HIV/AIDS Not a Major Driver.

Authors:  Bassey E Ekeng; Kevin Edem; Ikechukwu Amamilo; Zachary Panos; David Denning; Rita O Oladele
Journal:  J Fungi (Basel)       Date:  2021-06-30
  8 in total

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