Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Dopamine transporter (DAT) imaging in Parkinson's disease and related disorders.

Literature DB >> 34910248

Dopamine transporter (DAT) imaging in Parkinson's disease and related disorders.

Abstract

This review gives an insight into the beginnings of dopamine transporter (DAT) imaging in the early 1990s, focussing on single photon emission tomography (SPECT). The development of the method and its consolidation as a now widely used clinical tool is described. The role of DAT-SPECT in the diagnosis and differential diagnosis of PD, atypical parkinsonian syndromes and several other different neurological disorders is reviewed. Finally the clinical research using DAT-SPECT as a biomarker for the progression of PD, for the detection of a preclinical dopaminergic lesion and its correlation with neuropathological findings is outlined.

Entities: Chemical

Keywords: Atypical parkinsonian syndromes; DAT-SPECT; Dopaminergic imaging; PD progression; Parkinson’s disease (PD)

Mesh：

Substances：

Year: 2021 PMID： 34910248 DOI： 10.1007/s00702-021-02452-7

Source DB: PubMed Journal: J Neural Transm (Vienna) ISSN： 0300-9564 Impact factor: 3.850

Keyword Cloud
References

85 in total

1. Accurate differentiation of parkinsonism and essential tremor using visual assessment of [123I]-FP-CIT SPECT imaging: the [123I]-FP-CIT study group.

Authors: T S Benamer; J Patterson; D G Grosset; J Booij; K de Bruin; E van Royen; J D Speelman; M H Horstink; H J Sips; R A Dierckx; J Versijpt; D Decoo; C Van Der Linden; D M Hadley; M Doder; A J Lees; D C Costa; S Gacinovic; W H Oertel; O Pogarell; H Hoeffken; K Joseph; K Tatsch; J Schwarz; V Ries
Journal: Mov Disord Date: 2000-05 Impact factor: 10.338

2. [125I]RTI-55: a potent ligand for dopamine transporters.

Authors: J W Boja; A Patel; F I Carroll; M A Rahman; A Philip; A H Lewin; T A Kopajtic; M J Kuhar
Journal: Eur J Pharmacol Date: 1991-02-26 Impact factor: 4.432

3. Reduced Scan Time in 123I-FP-CIT SPECT Imaging Using a Large-Field Cadmium-Zinc-Telluride Camera.

Authors: Alexandre Bani Sadr; Nathalie Testart; Perrine Tylski; Christian Scheiber
Journal: Clin Nucl Med Date: 2019-07 Impact factor: 7.794

4. [123I]FP-CIT SPECT shows a pronounced decline of striatal dopamine transporter labelling in early and advanced Parkinson's disease.

Authors: J Booij; G Tissingh; G J Boer; J D Speelman; J C Stoof; A G Janssen; E C Wolters; E A van Royen
Journal: J Neurol Neurosurg Psychiatry Date: 1997-02 Impact factor: 10.154

5. In vivo evaluation of striatal dopamine reuptake sites using 11C-nomifensine and positron emission tomography.

Authors: S M Aquilonius; K Bergström; S A Eckernäs; P Hartvig; K L Leenders; H Lundquist; G Antoni; A Gee; A Rimland; J Uhlin
Journal: Acta Neurol Scand Date: 1987-10 Impact factor: 3.209

6. Correlation of Parkinson's disease severity and duration with 123I-FP-CIT SPECT striatal uptake.

Authors: H T Benamer; J Patterson; D J Wyper; D M Hadley; G J Macphee; D G Grosset
Journal: Mov Disord Date: 2000-07 Impact factor: 10.338

7. Imaging of dopamine transporters with iodine-123-beta-CIT and SPECT in Parkinson's disease.

Authors: S Asenbaum; T Brücke; W Pirker; I Podreka; P Angelberger; S Wenger; C Wöber; C Müller; L Deecke
Journal: J Nucl Med Date: 1997-01 Impact factor: 10.057

8. Prospective study of presynaptic dopaminergic imaging in patients with mild parkinsonism and tremor disorders: part 1. Baseline and 3-month observations.

Authors: Hani T S Benamer; Wolfgang H Oertel; Jim Patterson; Donald M Hadley; Oliver Pogarell; H Höffken; A Gerstner; Donald G Grosset
Journal: Mov Disord Date: 2003-09 Impact factor: 10.338

9. [123I]beta-CIT and SPECT in essential tremor and Parkinson's disease.

Authors: S Asenbaum; W Pirker; P Angelberger; G Bencsits; M Pruckmayer; T Brücke
Journal: J Neural Transm (Vienna) Date: 1998 Impact factor: 3.575