Literature DB >> 3490583

Effects of mutations within the 3' orf open reading frame region of human T-cell lymphotropic virus type III (HTLV-III/LAV) on replication and cytopathogenicity.

E Terwilliger, J G Sodroski, C A Rosen, W A Haseltine.   

Abstract

Mutations that eliminated the ability of the human T-cell lymphotropic virus type III to produce the 27-kilodalton 3' orf product did not eliminate the ability of the virus to replicate in and kill T4+ cells. A mutant carrying a mutation that deleted carboxy-terminal sequences from the envelope gene as well as the 3' orf sequences retained the ability to kill T4+ lymphocytes, but had a retarded replication rate.

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Year:  1986        PMID： 3490583      PMCID： PMC288951          DOI： 10.1128/JVI.60.2.754-760.1986

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  30 in total

1.  Nucleotide sequence of the visna lentivirus: relationship to the AIDS virus.

Authors:  P Sonigo; M Alizon; K Staskus; D Klatzmann; S Cole; O Danos; E Retzel; P Tiollais; A Haase; S Wain-Hobson
Journal:  Cell       Date:  1985-08       Impact factor: 41.582

2.  Complete nucleotide sequence of the AIDS virus, HTLV-III.

Authors:  L Ratner; W Haseltine; R Patarca; K J Livak; B Starcich; S F Josephs; E R Doran; J A Rafalski; E A Whitehorn; K Baumeister
Journal:  Nature       Date:  1985 Jan 24-30       Impact factor: 49.962

3.  Nucleotide sequence of the AIDS virus, LAV.

Authors:  S Wain-Hobson; P Sonigo; O Danos; S Cole; M Alizon
Journal:  Cell       Date:  1985-01       Impact factor: 41.582

4.  Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus.

Authors:  M A Muesing; D H Smith; C D Cabradilla; C V Benton; L A Lasky; D J Capon
Journal:  Nature       Date:  1985 Feb 7-13       Impact factor: 49.962

5.  Infection of HTLV-III/LAV in HTLV-I-carrying cells MT-2 and MT-4 and application in a plaque assay.

Authors:  S Harada; Y Koyanagi; N Yamamoto
Journal:  Science       Date:  1985-08-09       Impact factor: 47.728

6.  A new HTLV-III/LAV encoded antigen detected by antibodies from AIDS patients.

Authors:  J S Allan; J E Coligan; T H Lee; M F McLane; P J Kanki; J E Groopman; M Essex
Journal:  Science       Date:  1985-11-15       Impact factor: 47.728

Review 7.  AIDS--an immunologic reevaluation.

Authors:  M Seligmann; L Chess; J L Fahey; A S Fauci; P J Lachmann; J L'Age-Stehr; J Ngu; A J Pinching; F S Rosen; T J Spira
Journal:  N Engl J Med       Date:  1984-11-15       Impact factor: 91.245

8.  HTLV-III infection in brains of children and adults with AIDS encephalopathy.

Authors:  G M Shaw; M E Harper; B H Hahn; L G Epstein; D C Gajdusek; R W Price; B A Navia; C K Petito; C J O'Hara; J E Groopman
Journal:  Science       Date:  1985-01-11       Impact factor: 47.728

9.  Characterization of a continuous T-cell line susceptible to the cytopathic effects of the acquired immunodeficiency syndrome (AIDS)-associated retrovirus.

Authors:  T Folks; S Benn; A Rabson; T Theodore; M D Hoggan; M Martin; M Lightfoote; K Sell
Journal:  Proc Natl Acad Sci U S A       Date:  1985-07       Impact factor: 11.205

10.  A molecular clone of HTLV-III with biological activity.

Authors:  A G Fisher; E Collalti; L Ratner; R C Gallo; F Wong-Staal
Journal:  Nature       Date:  1985 Jul 18-24       Impact factor: 49.962
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  87 in total

1.  The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages.

Authors:  N Hattori; F Michaels; K Fargnoli; L Marcon; R C Gallo; G Franchini
Journal:  Proc Natl Acad Sci U S A       Date:  1990-10       Impact factor: 11.205

Review 2.  Mechanism of action of regulatory proteins encoded by complex retroviruses.

Authors:  B R Cullen
Journal:  Microbiol Rev       Date:  1992-09

3.  Chicken ovalbumin upstream promoter transcription factor binds to a negative regulatory region in the human immunodeficiency virus type 1 long terminal repeat.

Authors:  A J Cooney; S Y Tsai; B W O'Malley; M J Tsai
Journal:  J Virol       Date:  1991-06       Impact factor: 5.103

4.  Expression of nef, vpu, CA and CD4 during the infection of lymphoid and monocytic cell lines with HIV-1.

Authors:  T Schneider; P Hildebrandt; K Rokos; U Schubert; W Rönspeck; C Grund; A Beck; R Blesken; G Kulins; H Oldenburg
Journal:  Arch Virol       Date:  1992       Impact factor: 2.574

5.  Generation and characterization of the human immunodeficiency virus type 1 mutants.

Authors:  A Adachi; N Ono; H Sakai; K Ogawa; R Shibata; T Kiyomasu; H Masuike; S Ueda
Journal:  Arch Virol       Date:  1991       Impact factor: 2.574

6.  Gag-Pol supplied in trans is efficiently packaged and supports viral function in human immunodeficiency virus type 1.

Authors:  M K Hill; C W Hooker; D Harrich; S M Crowe; J Mak
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

7.  Expression and cellular localization of the Nef protein from human immunodeficiency virus-1 in stably transfected B-cells.

Authors:  N Kienzle; M Bachmann; W E Müller; N Müller-Lantzsch
Journal:  Arch Virol       Date:  1992       Impact factor: 2.574

8.  Evolution of human immunodeficiency virus type 1 nef and long terminal repeat sequences over 4 years in vivo and in vitro.

Authors:  S Delassus; R Cheynier; S Wain-Hobson
Journal:  J Virol       Date:  1991-01       Impact factor: 5.103

9.  Replication in vitro and in vivo of an equine infectious anemia virus mutant deficient in dUTPase activity.

Authors:  D L Lichtenstein; K E Rushlow; R F Cook; M L Raabe; C J Swardson; G J Kociba; C J Issel; R C Montelaro
Journal:  J Virol       Date:  1995-05       Impact factor: 5.103

10.  Human immunodeficiency virus type 1 Nef associates with a cellular serine kinase in T lymphocytes.

Authors:  E T Sawai; A Baur; H Struble; B M Peterlin; J A Levy; C Cheng-Mayer
Journal:  Proc Natl Acad Sci U S A       Date:  1994-02-15       Impact factor: 11.205
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