Literature DB >> 34897954

An ongoing science-society-ethics experiment: The human challenge trial debate in COVID-19 pandemic: The human challenge trial debate in COVID-19 pandemic.

Sonia M R Vasconcelos1,2, Angela Esher3, Carmen Penido4, Cleide Lima2, Karina A Rocha1, Maria Júlia M Antunes1, Mariana D Ribeiro1, Marlise Pedrotti1.   

Abstract

Human challenge trials to deliberately infect volunteers with SARS-CoV-2 should inspire wider debates about research ethics and participants' motivations to take part in such studies.
© 2021 The Authors.

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Mesh：

Year:  2021        PMID： 34897954      PMCID： PMC8728609          DOI： 10.15252/embr.202154184

Source DB:  PubMed          Journal:  EMBO Rep        ISSN： 1469-221X            Impact factor:   8.807


  10 in total

1.  Science and ethics. As research and technology are changing society and the way we live, scientists can no longer claim that science is neutral but must consider the ethical and social aspects of their work.

Authors:  M Iaccarino
Journal:  EMBO Rep       Date:  2001-09       Impact factor: 8.807

2.  Getting scientists to think about what they are doing.

Authors:  J Ziman
Journal:  Sci Eng Ethics       Date:  2001-04       Impact factor: 3.525

3.  Edward Jenner and the history of smallpox and vaccination.

Authors:  Stefan Riedel
Journal:  Proc (Bayl Univ Med Cent)       Date:  2005-01

4.  No PhDs needed: how citizen science is transforming research.

Authors:  Aisling Irwin
Journal:  Nature       Date:  2018-10       Impact factor: 49.962

5.  Opinion: For now, it's unethical to use human challenge studies for SARS-CoV-2 vaccine development.

Authors:  Jeffrey P Kahn; Leslie Meltzer Henry; Anna C Mastroianni; Wilbur H Chen; Ruth Macklin
Journal:  Proc Natl Acad Sci U S A       Date:  2020-10-29       Impact factor: 11.205

6.  Exploring Risks of Human Challenge Trials For COVID-19.

Authors:  David Manheim; Witold Wiȩcek; Virginia Schmit; Josh Morrison
Journal:  Risk Anal       Date:  2021-05-04       Impact factor: 4.000

7.  When could human challenge trials be deployed to combat emerging infectious diseases? Lessons from the case of a Zika virus human challenge trial.

Authors:  Ricardo Palacios; Seema K Shah
Journal:  Trials       Date:  2019-12-19       Impact factor: 2.279

8.  Patterns of smallpox mortality in London, England, over three centuries.

Authors:  Olga Krylova; David J D Earn
Journal:  PLoS Biol       Date:  2020-12-21       Impact factor: 8.029

9.  Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.

Authors:  Hongchao Pan; Richard Peto; Ana-Maria Henao-Restrepo; Marie-Pierre Preziosi; Vasee Sathiyamoorthy; Quarraisha Abdool Karim; Marissa M Alejandria; César Hernández García; Marie-Paule Kieny; Reza Malekzadeh; Srinivas Murthy; K Srinath Reddy; Mirta Roses Periago; Pierre Abi Hanna; Florence Ader; Abdullah M Al-Bader; Almonther Alhasawi; Emma Allum; Athari Alotaibi; Carlos A Alvarez-Moreno; Sheila Appadoo; Abdullah Asiri; Pål Aukrust; Andreas Barratt-Due; Samir Bellani; Mattia Branca; Heike B C Cappel-Porter; Nery Cerrato; Ting S Chow; Najada Como; Joe Eustace; Patricia J García; Sheela Godbole; Eduardo Gotuzzo; Laimonas Griskevicius; Rasha Hamra; Mariam Hassan; Mohamed Hassany; David Hutton; Irmansyah Irmansyah; Ligita Jancoriene; Jana Kirwan; Suresh Kumar; Peter Lennon; Gustavo Lopardo; Patrick Lydon; Nicola Magrini; Teresa Maguire; Suzana Manevska; Oriol Manuel; Sibylle McGinty; Marco T Medina; María L Mesa Rubio; Maria C Miranda-Montoya; Jeremy Nel; Estevao P Nunes; Markus Perola; Antonio Portolés; Menaldi R Rasmin; Aun Raza; Helen Rees; Paula P S Reges; Chris A Rogers; Kolawole Salami; Marina I Salvadori; Narvina Sinani; Jonathan A C Sterne; Milena Stevanovikj; Evelina Tacconelli; Kari A O Tikkinen; Sven Trelle; Hala Zaid; John-Arne Røttingen; Soumya Swaminathan
Journal:  N Engl J Med       Date:  2020-12-02       Impact factor: 91.245

10.  Why Challenge Trials of SARS-CoV-2 Vaccines Could Be Ethical Despite Risk of Severe Adverse Events.

Authors:  Nir Eyal
Journal:  Ethics Hum Res       Date:  2020-05-22
  10 in total

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