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Literature DB >> 34895514

AAV-mediated gene editing lights up the lung.

Ziying Yan¹, Thomas J Lynch², John F Engelhardt³.

Abstract

Entities: Chemical

Mesh：

Year: 2021 PMID： 34895514 PMCID： PMC8753516 DOI： 10.1016/j.ymthe.2021.12.003

Source DB: PubMed Journal: Mol Ther ISSN： 1525-0016 Impact factor: 11.454

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References

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6 in total

1. Hybrid adeno-associated virus bearing nonhomologous inverted terminal repeats enhances dual-vector reconstruction of minigenes in vivo.

Authors: Ziying Yan; Diana C M Lei-Butters; Yulong Zhang; Roman Zak; John F Engelhardt
Journal: Hum Gene Ther Date: 2007-01 Impact factor: 5.695

2. In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration.

Authors: Keiichiro Suzuki; Yuji Tsunekawa; Reyna Hernandez-Benitez; Jun Wu; Jie Zhu; Euiseok J Kim; Fumiyuki Hatanaka; Mako Yamamoto; Toshikazu Araoka; Zhe Li; Masakazu Kurita; Tomoaki Hishida; Mo Li; Emi Aizawa; Shicheng Guo; Song Chen; April Goebl; Rupa Devi Soligalla; Jing Qu; Tingshuai Jiang; Xin Fu; Maryam Jafari; Concepcion Rodriguez Esteban; W Travis Berggren; Jeronimo Lajara; Estrella Nuñez-Delicado; Pedro Guillen; Josep M Campistol; Fumio Matsuzaki; Guang-Hui Liu; Pierre Magistretti; Kun Zhang; Edward M Callaway; Kang Zhang; Juan Carlos Izpisua Belmonte
Journal: Nature Date: 2016-11-16 Impact factor: 49.962

AAV-mediated gene editing lights up the lung.

1. Hybrid adeno-associated virus bearing nonhomologous inverted terminal repeats enhances dual-vector reconstruction of minigenes in vivo.

2. In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration.

3. Human gene targeting by adeno-associated virus vectors is enhanced by DNA double-strand breaks.

4. Ciliated epithelial cell lifespan in the mouse trachea and lung.

5. Analysis of adeno-associated virus progenitor cell transduction in mouse lung.

6. AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway.