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Literature DB >> 3489070

MPTP toxicity: clinical features.

Abstract

MPTP causes acute irreversible Parkinsonism in man that mimics the idiopathic condition exactly. It is therefore a better model of the naturally occurring disease than previously described cases secondary to other chemicals or viruses.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1986 PMID： 3489070

Source DB: PubMed Journal: J Neural Transm Suppl ISSN： 0303-6995

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Cited

8 in total

Review 1. Neurotoxins as Preclinical Models for Parkinson's Disease.

Authors: Juan Segura-Aguilar
Journal: Neurotox Res Date: 2018-01-08 Impact factor: 3.911

2. Neurotoxin mechanisms and processes relevant to Parkinson's disease: an update.

Authors: Juan Segura-Aguilar; Richard M Kostrzewa
Journal: Neurotox Res Date: 2015-01-29 Impact factor: 3.911

3. On the Role of DT-Diaphorase Inhibition in Aminochrome-Induced Neurotoxicity In Vivo.

Authors: Andrea Herrera-Soto; Gabriela Díaz-Veliz; Sergio Mora; Patricia Muñoz; Pablo Henny; Harry W M Steinbusch; Juan Segura-Aguilar
Journal: Neurotox Res Date: 2017-03-11 Impact factor: 3.911

4. Protective Effects of Crude Plant Extracts against Aminochrome-induced toxicity in Human Astrocytoma Cells: Implications for Parkinson's Disease.

Authors: Viviane L Ndam Ngoungoure; Patricia Muñoz; Yousef Tizabi; Raul Valdes; Paul Fewou Moundipa; Juan Segura-Aguilar
Journal: Clin Pharmacol Transl Med Date: 2019-04-08

5. Can we conclude a potential therapeutic action for Parkinson's disease by using postmortem tissue and a preclinical model based on an exogenous neurotoxin?

Authors: Juan Segura-Aguilar
Journal: Cell Death Dis Date: 2018-07-03 Impact factor: 8.469

MPTP toxicity: clinical features.

Review 1. Neurotoxins as Preclinical Models for Parkinson's Disease.

2. Neurotoxin mechanisms and processes relevant to Parkinson's disease: an update.

3. On the Role of DT-Diaphorase Inhibition in Aminochrome-Induced Neurotoxicity In Vivo.

4. Protective Effects of Crude Plant Extracts against Aminochrome-induced toxicity in Human Astrocytoma Cells: Implications for Parkinson's Disease.

5. Can we conclude a potential therapeutic action for Parkinson's disease by using postmortem tissue and a preclinical model based on an exogenous neurotoxin?

6. State and perspectives on flavonoid neuroprotection against aminochrome-induced neurotoxicity.

Review 7. Astrocytes protect dopaminergic neurons against aminochrome neurotoxicity.

8. Microbiota and Other Preventive Strategies and Non-genetic Risk Factors in Parkinson's Disease.