Literature DB >> 3489065

Self-sparing of long-term in vitro-cloned or uncloned cytotoxic T lymphocytes.

M F Luciani, J F Brunet, M Suzan, F Denizot, P Golstein.   

Abstract

At least some long-term in vitro-cultured cytotoxic T cell clones and uncloned cell populations are able, in the presence of Con A, to lyse other cells, to be lysed by other cells, but not to lyse themselves. This as-yet-unexplained result may have implications as to the mechanism of T cell-mediated cytotoxicity.

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Year:  1986        PMID： 3489065      PMCID： PMC2188387          DOI： 10.1084/jem.164.3.962

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  5 in total

1.  Studies on the mechanism of lymphocyte-mediated cytolysis. IX. Relationships between antigen recognition and lytic expression in killer T cells.

Authors:  R C Kuppers; C S Henney
Journal:  J Immunol       Date:  1977-01       Impact factor: 5.422

2.  Interactions between MHC-encoded products and cloned T-cells. I. Fine specificity of induction of proliferation and lysis.

Authors:  F Albert; M Buferne; C Boyer; A M Schmitt-Verhulst
Journal:  Immunogenetics       Date:  1982       Impact factor: 2.846

3.  Characterization of an Lyt-1+ cytolytic T-cell clone specific for a polymorphic domain of the I-Ak molecule.

Authors:  A Pierres; A M Schmitt-Verhulst; M Buferne; P Golstein; M Pierres
Journal:  Scand J Immunol       Date:  1982-06       Impact factor: 3.487

4.  Cytolytic T cell hybridomas. I. Interleukin 2-independent noncytolytic variants.

Authors:  W Haas; P Kisielow
Journal:  Eur J Immunol       Date:  1985-08       Impact factor: 5.532

5.  Is the T-cell receptor involved in T-cell killing?

Authors:  A Lanzavecchia
Journal:  Nature       Date:  1986 Feb 27-Mar 5       Impact factor: 49.962
  5 in total
  9 in total

1.  The lysis of cytotoxic T lymphocytes and their blasts by cytotoxic T lymphocytes.

Authors:  B Schick; G Berke
Journal:  Immunology       Date:  1990-11       Impact factor: 7.397

2.  Influenza peptide-induced self-lysis and down-regulation of cloned cytotoxic T cells.

Authors:  R M Pemberton; D C Wraith; B A Askonas
Journal:  Immunology       Date:  1990-06       Impact factor: 7.397

3.  Resistance of cytotoxic T lymphocytes to lysis by a clone of cytotoxic T lymphocytes.

Authors:  D M Kranz; H N Eisen
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

4.  Target cell death triggered by cytotoxic T lymphocytes: a target cell mutant distinguishes passive pore formation and active cell suicide mechanisms.

Authors:  D S Ucker; J D Wilson; L D Hebshi
Journal:  Mol Cell Biol       Date:  1994-01       Impact factor: 4.272

5.  Mouse lymphoblasts lose their immunogenicity and susceptibility to specific cytotoxic T lymphocyte lysis during maintenance in culture.

Authors:  B Leshem; D Brass
Journal:  Immunology       Date:  1998-11       Impact factor: 7.397

6.  Calcium ion concentrations and DNA fragmentation in target cell destruction by murine cloned cytotoxic T lymphocytes.

Authors:  N L Allbritton; C R Verret; R C Wolley; H N Eisen
Journal:  J Exp Med       Date:  1988-02-01       Impact factor: 14.307

7.  Resistance of cytotoxic T lymphocytes to the lytic effects of their toxic granules.

Authors:  C R Verret; A A Firmenich; D M Kranz; H N Eisen
Journal:  J Exp Med       Date:  1987-11-01       Impact factor: 14.307

8.  Resistance of cloned cytotoxic T lymphocytes to cell-mediated cytotoxicity.

Authors:  A Blakely; K Gorman; H Ostergaard; K Svoboda; C C Liu; J D Young; W R Clark
Journal:  J Exp Med       Date:  1987-10-01       Impact factor: 14.307

9.  Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation.

Authors:  Kithiganahalli N Balaji; Norbert Schaschke; Werner Machleidt; Marta Catalfamo; Pierre A Henkart
Journal:  J Exp Med       Date:  2002-08-19       Impact factor: 14.307
  9 in total

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