Literature DB >> 3487831

Transforming growth factor-beta: biological function and chemical structure.

M B Sporn, A B Roberts, L M Wakefield, R K Assoian.   

Abstract

Transforming growth factor-beta (TGF-beta) is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGF-beta and essentially all of them have specific receptors for this peptide. TGF-beta regulates the actions of many other peptide growth factors and determines a positive or negative direction of their effects. Its marked ability to enhance formation of connective tissue in vivo suggests several therapeutic applications.

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Year:  1986        PMID： 3487831     DOI： 10.1126/science.3487831

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  201 in total

1.  Extraction and purification of TGFbeta and its effect on the induction of apoptosis of hepatocytes.

Authors:  X H Si; L J Yang
Journal:  World J Gastroenterol       Date:  2001-08       Impact factor: 5.742

2.  Activation of the transforming growth factor beta pathway in bacterial otitis media.

Authors:  Yun-Woo Lee; Yunju Chung; Steven K Juhn; Youngki Kim; Jizhen Lin
Journal:  Ann Otol Rhinol Laryngol       Date:  2011-03       Impact factor: 1.547

Review 3.  The paracrine role of Sertoli cells on Leydig cell function.

Authors:  H Lejeune; M Skalli; P G Chatelain; O Avallet; J M Saez
Journal:  Cell Biol Toxicol       Date:  1992 Jul-Sep       Impact factor: 6.691

4.  Effects of subcultivation and culture medium on differentiation of human fetal cardiac myocytes.

Authors:  B I Goldman; J Wurzel
Journal:  In Vitro Cell Dev Biol       Date:  1992-02

5.  Active multilayered capsules for in vivo bone formation.

Authors:  S Facca; C Cortez; C Mendoza-Palomares; N Messadeq; A Dierich; A P R Johnston; D Mainard; J-C Voegel; F Caruso; N Benkirane-Jessel
Journal:  Proc Natl Acad Sci U S A       Date:  2010-02-16       Impact factor: 11.205

6.  Growth suppression of transformed cells by a human placental extract not related to transforming growth factor beta.

Authors:  J L Klein; E Hamel; J L Tayot; H Yamasaki
Journal:  J Cancer Res Clin Oncol       Date:  1991       Impact factor: 4.553

Review 7.  Protein factors which regulate cell motility.

Authors:  E M Rosen; I D Goldberg
Journal:  In Vitro Cell Dev Biol       Date:  1989-12

8.  TGF-beta inhibits the in vitro induction of lymphokine-activated killing activity.

Authors:  E A Grimm; W L Crump; A Durett; J P Hester; S Lagoo-Deenadalayan; L B Owen-Schaub
Journal:  Cancer Immunol Immunother       Date:  1988       Impact factor: 6.968

9.  Inhibition of Nb2 T-lymphoma cell growth by transforming growth factor-beta.

Authors:  E J Rayhel; D A Prentice; P S Tabor; W H Flurkey; R W Geib; R F Laherty; S B Schnitzer; R Chen; J P Hughes
Journal:  Biochem J       Date:  1988-07-01       Impact factor: 3.857

10.  Release of interleukin 1 inhibitory activity (contra-IL-1) by human monocyte-derived macrophages infected with human immunodeficiency virus in vitro and in vivo.

Authors:  R M Locksley; S Crowe; M D Sadick; F P Heinzel; K D Gardner; M S McGrath; J Mills
Journal:  J Clin Invest       Date:  1988-12       Impact factor: 14.808
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