Literature DB >> 3487540

Mutations affecting expression and maintenance of genes encoding the serotype b capsule of Haemophilus influenzae.

S Ely, J Tippett, J S Kroll, E R Moxon.   

Abstract

Deletion mutagenesis analysis of a duplicated gene necessary for Haemophilus influenzae serotype b capsule expression showed that only one functional copy of this gene is required for capsule production and for virulence in infant rats. Mutant strains generated in this study differed from each other and from the parental strain in their ability to maintain the large tandem duplication which contains the genes involved in serotype b capsule expression.

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Year:  1986        PMID： 3487540      PMCID： PMC212838          DOI： 10.1128/jb.167.1.44-48.1986

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  14 in total

1.  Haemophilus influenzae meningitis in infant rats after intranasal inoculation.

Authors:  E R Moxon; A L Smith; D R Averill; D H Smith
Journal:  J Infect Dis       Date:  1974-02       Impact factor: 5.226

2.  A complex of recombination and repair genes in Haemophilus influenzae.

Authors:  J K Setlow; M E Boling; K L Beattie; R F Kimball
Journal:  J Mol Biol       Date:  1972-07-21       Impact factor: 5.469

3.  Defined nongrowth media for stage II development of competence in Haemophilus influenzae.

Authors:  R M Herriott; E M Meyer; M Vogt
Journal:  J Bacteriol       Date:  1970-02       Impact factor: 3.490

4.  The bidirectional transfer of DNA and RNA to nitrocellulose or diazobenzyloxymethyl-paper.

Authors:  G E Smith; M D Summers
Journal:  Anal Biochem       Date:  1980-11-15       Impact factor: 3.365

5.  Indirect enzyme-linked immunosorbent assay for the quantitation of the type-specific antigen of Haemophilus influenzae b: a preliminary report.

Authors:  J Pepple; E R Moxon; R H Yolken
Journal:  J Pediatr       Date:  1980-08       Impact factor: 4.406

6.  Haemophilus influenzae in cultures of cerebrospinal fluid. Noncapsulated variants typable by immunofluorescence.

Authors:  B W Catlin
Journal:  Am J Dis Child       Date:  1970-09

7.  Genes involved in Haemophilus influenzae type b capsule expression are part of an 18-kilobase tandem duplication.

Authors:  S K Hoiseth; E R Moxon; R P Silver
Journal:  Proc Natl Acad Sci U S A       Date:  1986-02       Impact factor: 11.205

8.  Human serum activities against Hemophilus influenzae, type b.

Authors:  P Anderson; R B Johnston; D H Smith
Journal:  J Clin Invest       Date:  1972-01       Impact factor: 14.808

9.  Construction and characterization of new cloning vehicles. IV. Deletion derivatives of pBR322 and pBR325.

Authors:  X Soberon; L Covarrubias; F Bolivar
Journal:  Gene       Date:  1980-05       Impact factor: 3.688

10.  Production of Haemophilus influenzae b meningitis in infant rats by intraperitoneal inoculation.

Authors:  A L Smith; D H Smith; D R Averill; J Marino; E R Moxon
Journal:  Infect Immun       Date:  1973-08       Impact factor: 3.441
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  6 in total

1.  Identification and characterization of a serotype b-specific segment of the Haemophilus influenzae genome.

Authors:  S Ely; J Tippett; E R Moxon
Journal:  Infect Immun       Date:  1989-09       Impact factor: 3.441

2.  Capsulation and gene copy number at the cap locus of Haemophilus influenzae type b.

Authors:  J S Kroll; E R Moxon
Journal:  J Bacteriol       Date:  1988-02       Impact factor: 3.490

3.  A major crossreactive idiotype associated with human antibodies to the Haemophilus influenzae b polysaccharide. Expression in relation to age and immunoglobulin G subclass.

Authors:  A H Lucas; D M Granoff
Journal:  J Clin Invest       Date:  1990-04       Impact factor: 14.808

4.  Genes encoding high-molecular-weight adhesion proteins of nontypeable Haemophilus influenzae are part of gene clusters.

Authors:  S J Barenkamp; J W St Geme
Journal:  Infect Immun       Date:  1994-08       Impact factor: 3.441

5.  Cloning, expression, and DNA sequence analysis of genes encoding nontypeable Haemophilus influenzae high-molecular-weight surface-exposed proteins related to filamentous hemagglutinin of Bordetella pertussis.

Authors:  S J Barenkamp; E Leininger
Journal:  Infect Immun       Date:  1992-04       Impact factor: 3.441

6.  Immunization with high-molecular-weight adhesion proteins of nontypeable Haemophilus influenzae modifies experimental otitis media in chinchillas.

Authors:  S J Barenkamp
Journal:  Infect Immun       Date:  1996-04       Impact factor: 3.441
  6 in total

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