Literature DB >> 2788141

Identification and characterization of a serotype b-specific segment of the Haemophilus influenzae genome.

S Ely1, J Tippett, E R Moxon.   

Abstract

Within the region of the Haemophilus influenzae serotype b genome required for capsule expression, a 4.6-kilobase segment was cloned, used as a hybridization probe, and found to be specific for serotype b strains. Deletion mutagenesis within this segment defined a locus necessary for serotype b capsule production and another involved in maintenance of wild-type colony appearance.

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Year:  1989        PMID： 2788141      PMCID： PMC313552          DOI： 10.1128/iai.57.9.2926-2928.1989

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  14 in total

1.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

2.  Genetics of spontaneous, high-frequency loss of b capsule expression in Haemophilus influenzae.

Authors:  S K Hoiseth; C J Connelly; E R Moxon
Journal:  Infect Immun       Date:  1985-08       Impact factor: 3.441

3.  Capsular polymer of Haemophilus influenzae, type b. I. Structural characterization of the capsular polymer of strain Eagan.

Authors:  R M Crisel; R S Baker; D E Dorman
Journal:  J Biol Chem       Date:  1975-07-10       Impact factor: 5.157

4.  Genes involved in Haemophilus influenzae type b capsule expression are part of an 18-kilobase tandem duplication.

Authors:  S K Hoiseth; E R Moxon; R P Silver
Journal:  Proc Natl Acad Sci U S A       Date:  1986-02       Impact factor: 11.205

5.  Construction and characterization of new cloning vehicles. II. A multipurpose cloning system.

Authors:  F Bolivar; R L Rodriguez; P J Greene; M C Betlach; H L Heyneker; H W Boyer; J H Crosa; S Falkow
Journal:  Gene       Date:  1977       Impact factor: 3.688

6.  Human serum activities against Hemophilus influenzae, type b.

Authors:  P Anderson; R B Johnston; D H Smith
Journal:  J Clin Invest       Date:  1972-01       Impact factor: 14.808

7.  Cloning of chromosomal DNA from Haemophilus influenzae. Its use for studying the expression of type b capsule and virulence.

Authors:  E R Moxon; R A Deich; C Connelly
Journal:  J Clin Invest       Date:  1984-02       Impact factor: 14.808

8.  Construction and characterization of new cloning vehicles. IV. Deletion derivatives of pBR322 and pBR325.

Authors:  X Soberon; L Covarrubias; F Bolivar
Journal:  Gene       Date:  1980-05       Impact factor: 3.688

9.  Limited genetic diversity of Haemophilus influenzae (type b).

Authors:  I Allan; M R Loeb; E R Moxon
Journal:  Microb Pathog       Date:  1987-02       Impact factor: 3.738

10.  Production of Haemophilus influenzae b meningitis in infant rats by intraperitoneal inoculation.

Authors:  A L Smith; D H Smith; D R Averill; J Marino; E R Moxon
Journal:  Infect Immun       Date:  1973-08       Impact factor: 3.441
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  2 in total

1.  Capsulation in distantly related strains of Haemophilus influenzae type b: genetic drift and gene transfer at the capsulation locus.

Authors:  J S Kroll; E R Moxon
Journal:  J Bacteriol       Date:  1990-03       Impact factor: 3.490

2.  Interaction of capsulate Haemophilus influenzae with human airway mucosa in vitro.

Authors:  R C Read; A A Rutman; P K Jeffery; V J Lund; A P Brain; E R Moxon; P J Cole; R Wilson
Journal:  Infect Immun       Date:  1992-08       Impact factor: 3.441
  2 in total

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