Literature DB >> 34859241

Animal models of brain metastasis.

Lauritz Miarka1, Manuel Valiente1.   

Abstract

Modeling of metastatic disease in animal models is a critical resource to study the complexity of this multi-step process in a relevant system. Available models of metastatic disease to the brain are still far from ideal but they allow to address specific aspects of the biology or mimic clinically relevant scenarios. We not only review experimental models and their potential improvements but also discuss specific answers that could be obtained from them on unsolved aspects of clinical management.
© The Author(s) 2021. Published by Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology.

Entities:  

Keywords:  brain metastasis; experimental models; therapy; treatment toxicity

Year:  2021        PMID: 34859241      PMCID: PMC8633729          DOI: 10.1093/noajnl/vdab115

Source DB:  PubMed          Journal:  Neurooncol Adv        ISSN: 2632-2498


  90 in total

1.  Real-time imaging reveals the single steps of brain metastasis formation.

Authors:  Yvonne Kienast; Louisa von Baumgarten; Martin Fuhrmann; Wolfgang E F Klinkert; Roland Goldbrunner; Jochen Herms; Frank Winkler
Journal:  Nat Med       Date:  2009-12-20       Impact factor: 53.440

2.  Survival and prognostic factors in surgically treated brain metastases.

Authors:  Vasileios K Kavouridis; Maya Harary; Alexander F C Hulsbergen; Yu T Lo; David A Reardon; Ayal A Aizer; J Bryan Iorgulescu; Timothy R Smith
Journal:  J Neurooncol       Date:  2019-04-16       Impact factor: 4.130

3.  BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma.

Authors:  E Elizabeth Patton; Hans R Widlund; Jeffery L Kutok; Kamden R Kopani; James F Amatruda; Ryan D Murphey; Stephane Berghmans; Elizabeth A Mayhall; David Traver; Christopher D M Fletcher; Jon C Aster; Scott R Granter; A Thomas Look; Charles Lee; David E Fisher; Leonard I Zon
Journal:  Curr Biol       Date:  2005-02-08       Impact factor: 10.834

4.  AKT1 Activation Promotes Development of Melanoma Metastases.

Authors:  Joseph H Cho; James P Robinson; Rowan A Arave; William J Burnett; David A Kircher; Guo Chen; Michael A Davies; Allie H Grossmann; Matthew W VanBrocklin; Martin McMahon; Sheri L Holmen
Journal:  Cell Rep       Date:  2015-10-22       Impact factor: 9.423

5.  Divergent clonal selection dominates medulloblastoma at recurrence.

Authors:  A Sorana Morrissy; Livia Garzia; David J H Shih; Scott Zuyderduyn; Xi Huang; Patryk Skowron; Marc Remke; Florence M G Cavalli; Vijay Ramaswamy; Patricia E Lindsay; Salomeh Jelveh; Laura K Donovan; Xin Wang; Betty Luu; Kory Zayne; Yisu Li; Chelsea Mayoh; Nina Thiessen; Eloi Mercier; Karen L Mungall; Yusanne Ma; Kane Tse; Thomas Zeng; Karey Shumansky; Andrew J L Roth; Sohrab Shah; Hamza Farooq; Noriyuki Kijima; Borja L Holgado; John J Y Lee; Stuart Matan-Lithwick; Jessica Liu; Stephen C Mack; Alex Manno; K A Michealraj; Carolina Nor; John Peacock; Lei Qin; Juri Reimand; Adi Rolider; Yuan Y Thompson; Xiaochong Wu; Trevor Pugh; Adrian Ally; Mikhail Bilenky; Yaron S N Butterfield; Rebecca Carlsen; Young Cheng; Eric Chuah; Richard D Corbett; Noreen Dhalla; An He; Darlene Lee; Haiyan I Li; William Long; Michael Mayo; Patrick Plettner; Jenny Q Qian; Jacqueline E Schein; Angela Tam; Tina Wong; Inanc Birol; Yongjun Zhao; Claudia C Faria; José Pimentel; Sofia Nunes; Tarek Shalaby; Michael Grotzer; Ian F Pollack; Ronald L Hamilton; Xiao-Nan Li; Anne E Bendel; Daniel W Fults; Andrew W Walter; Toshihiro Kumabe; Teiji Tominaga; V Peter Collins; Yoon-Jae Cho; Caitlin Hoffman; David Lyden; Jeffrey H Wisoff; James H Garvin; Duncan S Stearns; Luca Massimi; Ulrich Schüller; Jaroslav Sterba; Karel Zitterbart; Stephanie Puget; Olivier Ayrault; Sandra E Dunn; Daniela P C Tirapelli; Carlos G Carlotti; Helen Wheeler; Andrew R Hallahan; Wendy Ingram; Tobey J MacDonald; Jeffrey J Olson; Erwin G Van Meir; Ji-Yeoun Lee; Kyu-Chang Wang; Seung-Ki Kim; Byung-Kyu Cho; Torsten Pietsch; Gudrun Fleischhack; Stephan Tippelt; Young Shin Ra; Simon Bailey; Janet C Lindsey; Steven C Clifford; Charles G Eberhart; Michael K Cooper; Roger J Packer; Maura Massimino; Maria Luisa Garre; Ute Bartels; Uri Tabori; Cynthia E Hawkins; Peter Dirks; Eric Bouffet; James T Rutka; Robert J Wechsler-Reya; William A Weiss; Lara S Collier; Adam J Dupuy; Andrey Korshunov; David T W Jones; Marcel Kool; Paul A Northcott; Stefan M Pfister; David A Largaespada; Andrew J Mungall; Richard A Moore; Nada Jabado; Gary D Bader; Steven J M Jones; David Malkin; Marco A Marra; Michael D Taylor
Journal:  Nature       Date:  2016-01-13       Impact factor: 49.962

6.  Preclinical Comparison of Osimertinib with Other EGFR-TKIs in EGFR-Mutant NSCLC Brain Metastases Models, and Early Evidence of Clinical Brain Metastases Activity.

Authors:  Peter Ballard; James W T Yates; Zhenfan Yang; Dong-Wan Kim; James Chih-Hsin Yang; Mireille Cantarini; Kathryn Pickup; Angela Jordan; Mike Hickey; Matthew Grist; Matthew Box; Peter Johnström; Katarina Varnäs; Jonas Malmquist; Kenneth S Thress; Pasi A Jänne; Darren Cross
Journal:  Clin Cancer Res       Date:  2016-07-19       Impact factor: 12.531

7.  Circulating Tumor Cells Exhibit Metastatic Tropism and Reveal Brain Metastasis Drivers.

Authors:  Amal Thomas; Teng Teng; Remi Klotz; Sung Min Han; Oihana Iriondo; Lin Li; Sara Restrepo-Vassalli; Alan Wang; Negeen Izadian; Matthew MacKay; Byoung-San Moon; Kevin J Liu; Sathish Kumar Ganesan; Grace Lee; Diane S Kang; Charlotte S Walmsley; Christopher Pinto; Michael F Press; Wange Lu; Janice Lu; Dejan Juric; Aditya Bardia; James Hicks; Bodour Salhia; Frank Attenello; Andrew D Smith; Min Yu
Journal:  Cancer Discov       Date:  2019-10-10       Impact factor: 38.272

Review 8.  Rodent models in neuroscience research: is it a rat race?

Authors:  Bart Ellenbroek; Jiun Youn
Journal:  Dis Model Mech       Date:  2016-10-01       Impact factor: 5.758

9.  Osimertinib or Platinum-Pemetrexed in EGFR T790M-Positive Lung Cancer.

Authors:  Tony S Mok; Yi-Long Wu; Myung-Ju Ahn; Marina C Garassino; Hye R Kim; Suresh S Ramalingam; Frances A Shepherd; Yong He; Hiroaki Akamatsu; Willemijn S M E Theelen; Chee K Lee; Martin Sebastian; Alison Templeton; Helen Mann; Marcelo Marotti; Serban Ghiorghiu; Vassiliki A Papadimitrakopoulou
Journal:  N Engl J Med       Date:  2016-12-06       Impact factor: 91.245

Review 10.  Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines.

Authors:  Manuel Valiente; Amanda E D Van Swearingen; Carey K Anders; Amos Bairoch; Adrienne Boire; Paula D Bos; Diana M Cittelly; Neta Erez; Gino B Ferraro; Dai Fukumura; Brunilde Gril; Meenhard Herlyn; Sheri L Holmen; Rakesh K Jain; Johanna A Joyce; Mihaela Lorger; Joan Massague; Josh Neman; Nicola R Sibson; Patricia S Steeg; Frits Thorsen; Leonie S Young; Damir Varešlija; Adina Vultur; Frances Weis-Garcia; Frank Winkler
Journal:  Cancer Res       Date:  2020-07-08       Impact factor: 12.701

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  3 in total

Review 1.  Towards updated understanding of brain metastasis.

Authors:  Shuncong Wang; Yuanbo Feng; Lei Chen; Jie Yu; Chantal Van Ongeval; Guy Bormans; Yue Li; Yicheng Ni
Journal:  Am J Cancer Res       Date:  2022-09-15       Impact factor: 5.942

2.  Patient-derived models of brain metastases recapitulate human disseminated disease.

Authors:  Claudia C Faria; Rita Cascão; Carlos Custódia; Eunice Paisana; Tânia Carvalho; Pedro Pereira; Rafael Roque; José Pimentel; José Miguéns; Isidro Cortes-Ciriano; João T Barata
Journal:  Cell Rep Med       Date:  2022-05-03

Review 3.  Liquid biopsies to occult brain metastasis.

Authors:  Asad Ur Rehman; Parvez Khan; Shailendra Kumar Maurya; Jawed A Siddiqui; Juan A Santamaria-Barria; Surinder K Batra; Mohd Wasim Nasser
Journal:  Mol Cancer       Date:  2022-05-10       Impact factor: 41.444

  3 in total

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