Literature DB >> 3485680

Natural and recombinant human interleukin 1-beta is cytotoxic for human melanoma cells.

L B Lachman, C A Dinarello, N D Llansa, I J Fidler.   

Abstract

Human peripheral blood monocytes stimulated with LPS were found to release an activity that was cytotoxic for the A375 melanoma. Biochemical and immunological characterization of the activity indicated that IL 1-beta was the cytotoxic agent. Human recombinant IL 1-beta, purified to homogeneity, was directly cytotoxic for A375. Tumor necrosis factor, also released by activated monocytes, was not cytotoxic for the A375 melanoma.

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Year:  1986        PMID： 3485680

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  46 in total

1.  Aberrant cytokine production from tenosynovium in dialysis associated amyloidosis.

Authors:  N Miyasaka; K Sato; Y Kitano; M Higaki; K Nishioka; K Ohta
Journal:  Ann Rheum Dis       Date:  1992-06       Impact factor: 19.103

Review 2.  Resistance of tumor cells to tumor necrosis factor.

Authors:  H M Shepard; G D Lewis
Journal:  J Clin Immunol       Date:  1988-09       Impact factor: 8.317

3.  Human monocytes selectively bind to cells expressing the tumorigenic phenotype.

Authors:  H Shimizu; D Wyatt; R D Knowles; C D Bucana; E J Stanbridge; E S Kleinerman
Journal:  Cancer Immunol Immunother       Date:  1989       Impact factor: 6.968

4.  Destruction of tumor cells by monokines released from activated human blood monocytes: evidence for parallel and additive effects of IL-1 and TNF.

Authors:  Y Ichinose; J Y Tsao; I J Fidler
Journal:  Cancer Immunol Immunother       Date:  1988       Impact factor: 6.968

5.  Mechanism of anaemia in rheumatoid arthritis: demonstration of raised interleukin 1 beta concentrations in anaemic patients and of interleukin 1 mediated suppression of normal erythropoiesis and proliferation of human erythroleukaemia (HEL) cells in vitro.

Authors:  C P Maury; L C Andersson; A M Teppo; S Partanen; E Juvonen
Journal:  Ann Rheum Dis       Date:  1988-12       Impact factor: 19.103

6.  Expression of genes for interleukin-1 alpha and tumour necrosis factor-alpha in newborn mice.

Authors:  M Lipoldová; V Holán
Journal:  Immunology       Date:  1990-05       Impact factor: 7.397

7.  Melanotropin receptors demonstrated in situ in human melanoma.

Authors:  J B Tatro; M Atkins; J W Mier; S Hardarson; H Wolfe; T Smith; M L Entwistle; S Reichlin
Journal:  J Clin Invest       Date:  1990-06       Impact factor: 14.808

8.  Tumor necrosis factor mediates endotoxic effects in mice.

Authors:  F Bauss; W Dröge; D N Männel
Journal:  Infect Immun       Date:  1987-07       Impact factor: 3.441

9.  Interleukin 1 mediated acceleration of type II collagen-induced arthritis: effects of anti-inflammatory or anti-arthritic drugs.

Authors:  J T Hom; V L Gliszczynski; H W Cole; A M Bendele
Journal:  Agents Actions       Date:  1991-07

10.  IL-1beta acts in synergy with endogenous IL-1beta in A375-S2 human melanoma cell apoptosis through mitochondrial pathway.

Authors:  Che Wang; Min-wei Wang; Shin-ichi Tashiro; Satoshi Onodera; Takashi Ikejima
Journal:  J Korean Med Sci       Date:  2005-08       Impact factor: 2.153
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