Literature DB >> 2354858

Expression of genes for interleukin-1 alpha and tumour necrosis factor-alpha in newborn mice.

M Lipoldová1, V Holán.   

Abstract

Spleen cells from newborn mice are immunologically non-reactive and do not respond by proliferation to T- or B-cell mitogens. However, they synthesize significant levels of mRNA for interleukin-1 alpha (IL-1 alpha) and tumour necrosis factor-alpha (TNF-alpha) after mitogen stimulation. Since these two cytokines mediate many protective activities in the body, they may be important in ensuring the survival of immunologically immature newborns.

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Year:  1990        PMID： 2354858      PMCID： PMC1384095     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  18 in total

1.  Suprression of local graft-versus-host reactions by mouse fetal and newborn spleen cells.

Authors:  A Skowron-Cendrzak; W Ptak
Journal:  Eur J Immunol       Date:  1976-06       Impact factor: 5.532

2.  A defect in the antigen-presenting function of macrophages from neonatal mice.

Authors:  C Y Lu; E G Calamai; E R Unanue
Journal:  Nature       Date:  1979-11-15       Impact factor: 49.962

3.  Functional development of the interacting cells in the immune response. I. Development of T cell and B cell function.

Authors:  M Q Chiscon; E S Golub
Journal:  J Immunol       Date:  1972-05       Impact factor: 5.422

4.  An endotoxin-induced serum factor that causes necrosis of tumors.

Authors:  E A Carswell; L J Old; R L Kassel; S Green; N Fiore; B Williamson
Journal:  Proc Natl Acad Sci U S A       Date:  1975-09       Impact factor: 11.205

5.  Analysis of T-cell receptor usage in activated T-cell clones from Hashimoto's thyroiditis and Graves' disease.

Authors:  M Lipoldova; M Londei; B Grubeck-Loebenstein; M Feldmann; M J Owen
Journal:  J Autoimmun       Date:  1989-02       Impact factor: 7.094

6.  Molecular cloning of mouse tumour necrosis factor cDNA and its eukaryotic expression.

Authors:  L Fransen; R Müller; A Marmenout; J Tavernier; J Van der Heyden; E Kawashima; A Chollet; R Tizard; H Van Heuverswyn; A Van Vliet
Journal:  Nucleic Acids Res       Date:  1985-06-25       Impact factor: 16.971

7.  Antitumor activity of murine tumor necrosis factor (TNF) against transplanted murine tumors and heterotransplanted human tumors in nude mice.

Authors:  K Haranaka; N Satomi; A Sakurai
Journal:  Int J Cancer       Date:  1984-08-15       Impact factor: 7.396

8.  Interferon-gamma enhances induction of lymphotoxin in recombinant interleukin 2-stimulated peripheral blood mononuclear cells.

Authors:  L P Svedersky; G E Nedwin; D V Goeddel; M A Palladino
Journal:  J Immunol       Date:  1985-03       Impact factor: 5.422

9.  Cloning and expression of murine interleukin-1 cDNA in Escherichia coli.

Authors:  P T Lomedico; U Gubler; C P Hellmann; M Dukovich; J G Giri; Y C Pan; K Collier; R Semionow; A O Chua; S B Mizel
Journal:  Nature       Date:  1984 Nov 29-Dec 5       Impact factor: 49.962

10.  Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

Authors:  J M Chirgwin; A E Przybyla; R J MacDonald; W J Rutter
Journal:  Biochemistry       Date:  1979-11-27       Impact factor: 3.162
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  1 in total

1.  Inability of mitogen-stimulated spleen cells from newborn mice to synthesize interleukin-2 receptors.

Authors:  M Lipoldová; A Zajícová; V Holán
Journal:  Immunology       Date:  1990-12       Impact factor: 7.397
  1 in total

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