Literature DB >> 34850260

[Imaging of oligometastatic disease in selected urologic cancers].

S A Koerber1, C A Fink1, K Dendl2,3, D Schmitt2, G Niegisch4, E Mamlins2, F L Giesel5.   

Abstract

BACKGROUND: Local treatment of the primary or metastatic sites in urologic malignancies is promising when compared to systemic therapy alone, leading to the definition of a potentially curative oligometastatic state.
OBJECTIVES: Comparison of imaging modalities regarding local and metastatic tumor sites in urologic cancers.
METHODS: Review of comparative trials addressing quality criteria of imaging modalities.
RESULTS: Depending on primary tumor and metastatic site, conventional imaging modalities such as computer tomography (CT) and bone scintigraphy still represent the standard of care in Germany. Due to superior quality criteria, hybrid-imaging techniques were widely adopted for oncological staging and particular due to the new PSMA-ligand (PSMA-PET/CT) in prostate cancer imaging. The development of new radioisotopes as well as their clinical application remains a focus of current research.
CONCLUSIONS: High-quality diagnostic imaging modalities lay the groundwork for a precise definition of an oligometastatic state. By enabling treatment of the entire tumor burden, a delay of systemic therapy, longer progression-free survival, or even curative treatment may become achievable.
© 2021. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.

Entities:  

Keywords:  Oligometastasis; Positron emission tomography; Prostate cancer; Renal cell cancer; Urothelial cancer

Mesh:

Year:  2021        PMID: 34850260     DOI: 10.1007/s00120-021-01708-0

Source DB:  PubMed          Journal:  Urologe A        ISSN: 0340-2592            Impact factor:   0.639


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Journal:  Br J Radiol       Date:  2017-12-07       Impact factor: 3.039

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