Literature DB >> 34824706

Autonomic Denervation Dermatitis: A Relatively Undocumented 'ADD'itional Complication of Total Knee Replacements and Other Surgeries Around the Knee.

Mandeep Singh Dhillon1, Karan Jindal1, Vijay D Shetty2, Prasoon Kumar1, Rajesh Kumar Rajnish3.   

Abstract

BACKGROUND: Infrapatellar branch of the saphenous nerve lies subcutaneously and supplies the anterolateral aspect of knee below the patella. It is extremely susceptible to iatrogenic injuries during the surgeries around the knee, mainly total knee replacements (TKRs). Post operatively the patients present with localised area of numbness and in some instances a traumatic eczematous reaction termed autonomous denervation dermatitis (ADD) is witnessed, leading to skin manifestations that range from a simple rash to extensive lesions.
METHODOLOGY: A review of literature was conducted with search of relevant articles from Medline (PubMed), Embase, and Scopus which discussed eczematous skin lesions secondary to total knee replacements. Additionally, we noted studies which described these lesions in other surgeries around the knee like arthroscopies and fracture fixations.
RESULTS: Eight studies including atleast one case after TKR were reviewed. There was only one cohort study while the remaining included case reports and small case series. There were 69 cases of ADD appearing after TKR. The appearance of the skin lesions was lateral to the incision in 30/34 operated knees and on both sides of the incision in four knees after TKRs. Bilateral lesions were seen in only six patients of TKRs. There was no functional limitation caused by these lesions and they resolved either spontaneously or after using topical steroids.
CONCLUSION: ADD is a relatively uncommonly reported complication of TKRs, which can reduce patient satisfaction and increase surgeon apprehension. Although all cases of nerve damage do not manifest as cutaneous lesions, steps to minimise the damage to the nerve intra operatively should be taken. The diagnosis requires a high index of suspicion, and should not be dispelled as a simple allergic reaction without adequate investigations. Patients should be counselled to alleviate unnecessary fear and apprehensions. © Indian Orthopaedics Association 2021.

Entities:  

Keywords:  ADD; Autosomal denervation dermatitis; Infra patellar branch; SKINTED; Saphenous nerve; Total knee replacements

Year:  2021        PMID: 34824706      PMCID: PMC8586114          DOI: 10.1007/s43465-021-00520-4

Source DB:  PubMed          Journal:  Indian J Orthop        ISSN: 0019-5413            Impact factor:   1.033


  21 in total

1.  The relationship of the infrapatellar branches of the saphenous nerve to arthroscopy portals and incisions for anterior cruciate ligament surgery. An anatomic study.

Authors:  C D Tifford; L Spero; T Luke; K D Plancher
Journal:  Am J Sports Med       Date:  2000 Jul-Aug       Impact factor: 6.202

2.  Methodological index for non-randomized studies (minors): development and validation of a new instrument.

Authors:  Karem Slim; Emile Nini; Damien Forestier; Fabrice Kwiatkowski; Yves Panis; Jacques Chipponi
Journal:  ANZ J Surg       Date:  2003-09       Impact factor: 1.872

3.  Explaining a hitherto nameless condition: 'SKINTED'.

Authors:  S B Verma; B S Mody
Journal:  Clin Exp Dermatol       Date:  2009-10       Impact factor: 3.470

4.  SKINTED: an autonomic denervation dermatitis.

Authors:  Yashdeep Singh Pathania; Saurabh Singh
Journal:  Int J Dermatol       Date:  2019-07-08       Impact factor: 2.736

5.  Anatomic study of infrapatellar branch of saphenous nerve in male cadavers.

Authors:  S G Kalthur; S Sumalatha; N Nair; A K Pandey; S Sequeria; L Shobha
Journal:  Ir J Med Sci       Date:  2014-02-18       Impact factor: 1.568

6.  Characterizing the Diagnosis and Treatment of Allergic Contact Dermatitis to 2-Octyl Cyanoacrylate Used for Skin Closure in Elective Orthopedic Surgery.

Authors:  Brian P Chalmers; Heath P Melugin; Peter K Sculco; Jennifer J Schoch; Rafael J Sierra; Mark W Pagnano; Michael J Stuart; Michael J Taunton
Journal:  J Arthroplasty       Date:  2017-07-18       Impact factor: 4.757

7.  Patient satisfaction after total knee arthroplasty: who is satisfied and who is not?

Authors:  Robert B Bourne; Bert M Chesworth; Aileen M Davis; Nizar N Mahomed; Kory D J Charron
Journal:  Clin Orthop Relat Res       Date:  2010-01       Impact factor: 4.176

Review 8.  The surgical anatomy of the infrapatellar branch of the saphenous nerve in relation to incisions for anteromedial knee surgery.

Authors:  A L A Kerver; M S Leliveld; D den Hartog; M H J Verhofstad; G J Kleinrensink
Journal:  J Bone Joint Surg Am       Date:  2013-12-04       Impact factor: 5.284

9.  A prospective randomized study in 20 patients undergoing bilateral TKA comparing midline incision to anterolateral incision.

Authors:  Rajesh N Maniar; Tushar Singhi; Arun Nanivadekar; Parul R Maniar; Jaivardhan Singh
Journal:  J Orthop Traumatol       Date:  2017-02-11

10.  Neuropathy Dermatitis following Surgical Nerve Injury.

Authors:  Khalifa E Sharquie; Adil A Noaimi; Ali S Alaboudi
Journal:  Case Rep Dermatol Med       Date:  2012-01-29
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