Literature DB >> 34824392

Navigating a new path to Nav1.7 for pain.

Katie Kingwell.   

Abstract

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Year:  2022        PMID： 34824392     DOI： 10.1038/d41573-021-00197-2

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  1 in total

1.  Selective targeting of NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents.

Authors:  Song Cai; Aubin Moutal; Jie Yu; Lindsey A Chew; Jörg Isensee; Reena Chawla; Kimberly Gomez; Shizhen Luo; Yuan Zhou; Aude Chefdeville; Cynthia Madura; Samantha Perez-Miller; Shreya Sai Bellampalli; Angie Dorame; David D Scott; Liberty François-Moutal; Zhiming Shan; Taylor Woodward; Vijay Gokhale; Andrea G Hohmann; Todd W Vanderah; Marcel Patek; May Khanna; Tim Hucho; Rajesh Khanna
Journal:  Sci Transl Med       Date:  2021-11-10       Impact factor: 19.319
  1 in total
  3 in total

1.  The Human SCN9A R185H Point Mutation Induces Pain Hypersensitivity and Spontaneous Pain in Mice.

Authors:  Yaping Xue; Mélanie Kremer; Maria Del Mar Muniz Moreno; Celeste Chidiac; Romain Lorentz; Marie-Christine Birling; Michel Barrot; Yann Herault; Claire Gaveriaux-Ruff
Journal:  Front Mol Neurosci       Date:  2022-06-13       Impact factor: 6.261

2.  Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in chronic constriction injury (CCI) rats.

Authors:  Jiahe Li; Harrison J Stratton; Sabina A Lorca; Peter M Grace; Rajesh Khanna
Journal:  Channels (Austin)       Date:  2022-12       Impact factor: 2.581

3.  Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces and prevents pain chronification in a mouse model of oxaliplatin-induced neuropathic pain.

Authors:  Kathryn Braden; Harrison J Stratton; Daniela Salvemini; Rajesh Khanna
Journal:  Neurobiol Pain       Date:  2021-12-27
  3 in total

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