| Literature DB >> 34818614 |
Emilio Salinas1, Terrence R Stanford2.
Abstract
The choice of where to look next is determined by both exogenous (bottom-up) and endogenous (top-down) factors, but details of their interaction and distinct contributions to target selection have remained elusive. Recent experiments with urgent choice tasks, in which stimuli are evaluated while motor plans are already advancing, have greatly clarified these contributions. Specifically, exogenous modulations associated with stimulus detection act rapidly and briefly (∼25 ms) to automatically halt and/or boost ongoing motor plans as per spatial congruence rules. These stereotypical modulations explain, in quantitative detail, characteristic features of many saccadic tasks (e.g. antisaccade, countermanding, saccadic-inhibition, gap, and double-step). Thus, the same low-level visuomotor interactions contribute to diverse oculomotor phenomena traditionally attributed to different neural mechanisms.Entities:
Mesh:
Year: 2021 PMID: 34818614 PMCID: PMC8688226 DOI: 10.1016/j.conb.2021.10.012
Source DB: PubMed Journal: Curr Opin Neurobiol ISSN: 0959-4388 Impact factor: 6.627