Literature DB >> 34814109

Case Report: Cerebral Phaeohyphomycosis Due to Chaetomium strumarium in a Child with Visceral Heterotaxy Syndrome.

Bárbara Cárdenas Del Castillo1, Jose Iván Castillo Bejarano2, Oscar DeLaGarza-Pineda3, José Ascención Arenas Ruiz4, Hiram Villanueva Lozano5, Rogelio de J Treviño-Rangel6, Gloria González M6, Joyce Marie García Martínez7.   

Abstract

Chaetomium sp. is a mold, member of the phylum Ascomycota. Clinical disease in humans is rare, particularly in children, for which only five cases have been reported. We report a 7-months-old female patient with a diagnosis of visceral heterotaxy syndrome who was admitted to a private center in Mexico. After two episodes of focal myoclonic seizure, a brain magnetic resonance imaging (MRI) revealed a right porencephalic cyst and a right frontal abscess with ventriculitis. Seventy-two hours after temporal abscesses drainage procedure, the culture showed a rapidly growing pale white fungal colony. Sequencing of internal transcribed spacer (ITS) and D1/D2 led to the identification of Chaetomium strumarium. Although Chaetomium sp. is a rare fungal infection in humans, clinicians should consider it as a plausible etiologic agent that can form brain abscess.

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Year:  2021        PMID: 34814109      PMCID: PMC8832948          DOI: 10.4269/ajtmh.21-0277

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  14 in total

1.  Chaetomium retinitis.

Authors:  Khalid F Tabbara; Keith Wedin; Saad Al Haddab
Journal:  Retin Cases Brief Rep       Date:  2010

2.  Cerebral phaeohyphomycosis caused by Chaetomium globosum in a renal transplant recipient.

Authors:  V Anandi; T J John; A Walter; J C Shastry; M K Lalitha; A A Padhye; L Ajello; F W Chandler
Journal:  J Clin Microbiol       Date:  1989-10       Impact factor: 5.948

Review 3.  Endoscopic ventriculo-cisterno-ventricular approach in the treatment of bilateral trapped temporal horn related to fungal infection in a child: case report and review of the literature.

Authors:  José Ascención Arenas-Ruiz; Horus Martinez-Maldonado; Vicente Gonzalez-Carranza; Samuel Torres-García; Fernando Chico-Ponce de Leon
Journal:  Childs Nerv Syst       Date:  2018-03-20       Impact factor: 1.475

4.  Phaeohyphomycosis in a tertiary care cancer center.

Authors:  Ronen Ben-Ami; Russell E Lewis; Issam I Raad; Dimitrios P Kontoyiannis
Journal:  Clin Infect Dis       Date:  2009-04-15       Impact factor: 9.079

Review 5.  Invasive chaetomium infection in two immunocompromised pediatric patients.

Authors:  Amal Al-Aidaroos; Ibrahim Bin-Hussain; Hassan El Solh; Amani Kofide; Sahar Thawadi; Asim Belgaumi; Ali Al Ahmari
Journal:  Pediatr Infect Dis J       Date:  2007-05       Impact factor: 2.129

Review 6.  Invasive mycotic infections caused by Chaetomium perlucidum, a new agent of cerebral phaeohyphomycosis.

Authors:  M A Barron; D A Sutton; R Veve; J Guarro; M Rinaldi; E Thompson; P J Cagnoni; K Moultney; N E Madinger
Journal:  J Clin Microbiol       Date:  2003-11       Impact factor: 5.948

7.  Combined methenamine-silver nitrate and hematoxylin & eosin stain for fungi in tissues.

Authors:  M Huppert; D J Oliver; S H Sun
Journal:  J Clin Microbiol       Date:  1978-11       Impact factor: 5.948

8.  Fatal cerebral mycoses caused by the ascomycete Chaetomium strumarium.

Authors:  S P Abbott; L Sigler; R McAleer; D A McGough; M G Rinaldi; G Mizell
Journal:  J Clin Microbiol       Date:  1995-10       Impact factor: 5.948

9.  ESCMID and ECMM joint clinical guidelines for the diagnosis and management of systemic phaeohyphomycosis: diseases caused by black fungi.

Authors:  A Chowdhary; J F Meis; J Guarro; G S de Hoog; S Kathuria; M C Arendrup; S Arikan-Akdagli; M Akova; T Boekhout; M Caira; J Guinea; A Chakrabarti; E Dannaoui; A van Diepeningen; T Freiberger; A H Groll; W W Hope; E Johnson; M Lackner; K Lagrou; F Lanternier; C Lass-Flörl; O Lortholary; J Meletiadis; P Muñoz; L Pagano; G Petrikkos; M D Richardson; E Roilides; A Skiada; A M Tortorano; A J Ullmann; P E Verweij; O A Cornely; M Cuenca-Estrella
Journal:  Clin Microbiol Infect       Date:  2014-04       Impact factor: 8.067

10.  The soil fungus Chaetomium in the human paranasal sinuses.

Authors:  A Aru; L Munk-Nielsen; B H Federspiel
Journal:  Eur Arch Otorhinolaryngol       Date:  1997       Impact factor: 3.236

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