Khalid F Tabbara1, Keith Wedin, Saad Al Haddab. 1. From the *Department of Surgery, Section of Ophthalmology, King Faisal Specialist Hospital and Research Centre; †The Eye Center and The Eye Foundation for Research in Ophthalmology, Riyadh, Saudi Arabia; and ‡The Wilmer Ophthalmological Institute of The Johns Hopkins University School of Medicine, Baltimore, Maryland.
Abstract
PURPOSE: To report a case of Chaetomium atrobrunneum retinitis in a patient with Hodgkin lymphoma. METHODS: We studied the ocular manifestations of an 11-year-old boy with retinitis. Biomicroscopy, ophthalmoscopy, and fundus photography were done. Magnetic resonance imaging of the brain was performed. A vitreous biopsy was subjected to viral, bacterial, and fungal cultures. RESULTS: Vitreous culture grew C. atrobrunneum. Magnetic resonance imaging showed multiple cerebral lesions consistent with an infectious process. The patient was given intravenous voriconazole and showed improvement of the ocular and central nervous system lesions. CONCLUSION: We report a case of central nervous system and ocular lesions by C. atrobrunneum. The retinitis was initially misdiagnosed as cytomegaloviral retinitis. Vitreous biopsy helped in the early diagnosis and prompt treatment of a life- and vision-threatening infection.
PURPOSE: To report a case of Chaetomium atrobrunneum retinitis in a patient with Hodgkin lymphoma. METHODS: We studied the ocular manifestations of an 11-year-old boy with retinitis. Biomicroscopy, ophthalmoscopy, and fundus photography were done. Magnetic resonance imaging of the brain was performed. A vitreous biopsy was subjected to viral, bacterial, and fungal cultures. RESULTS: Vitreous culture grew C. atrobrunneum. Magnetic resonance imaging showed multiple cerebral lesions consistent with an infectious process. The patient was given intravenous voriconazole and showed improvement of the ocular and central nervous system lesions. CONCLUSION: We report a case of central nervous system and ocular lesions by C. atrobrunneum. The retinitis was initially misdiagnosed as cytomegaloviral retinitis. Vitreous biopsy helped in the early diagnosis and prompt treatment of a life- and vision-threatening infection.
Authors: Bárbara Cárdenas Del Castillo; Jose Iván Castillo Bejarano; Oscar DeLaGarza-Pineda; José Ascención Arenas Ruiz; Hiram Villanueva Lozano; Rogelio de J Treviño-Rangel; Gloria González M; Joyce Marie García Martínez Journal: Am J Trop Med Hyg Date: 2021-11-22 Impact factor: 2.345