OBJECTIVES: To compare the rate of extraction space closure between periodontally accelerated osteogenic orthodontics (PAOO) using platelet-rich fibrin (PRF) (Group 1) and PAOO using demineralized bone xenograft (DMBM) (Group 2) and to compare the level of wound healing between the PRF group vs the DMBM group after PAOO. MATERIALS AND METHODS: A two-arm prospective single blind pilot study with a split-mouth design was used in which 14 patients requiring premolar extraction were divided into two groups: PRF and DMBM. En-masse space closure was carried out with using mini implants after the PAOO procedure. The amount of space closure was measured at five time points with 2-week intervals within 2 months. The gingival healing levels were assessed using early wound healing scores on the first postoperative day. RESULTS: The rate of extraction space closure was faster in the experimental quadrant at all time points (T1-T4) in the PRF group and at time points (T3, T4) in the DMBM group. Comparison between experimental quadrants showed a significant increase in the rate of space closure in the PRF group T1 to T3 (P < .05). The PRF group showed higher total early healing scores than the DMBM group. CONCLUSIONS: PRF, when used in the PAOO procedure, produces a faster rate of space closure with better early wound healing than DMBM.
OBJECTIVES: To compare the rate of extraction space closure between periodontally accelerated osteogenic orthodontics (PAOO) using platelet-rich fibrin (PRF) (Group 1) and PAOO using demineralized bone xenograft (DMBM) (Group 2) and to compare the level of wound healing between the PRF group vs the DMBM group after PAOO. MATERIALS AND METHODS: A two-arm prospective single blind pilot study with a split-mouth design was used in which 14 patients requiring premolar extraction were divided into two groups: PRF and DMBM. En-masse space closure was carried out with using mini implants after the PAOO procedure. The amount of space closure was measured at five time points with 2-week intervals within 2 months. The gingival healing levels were assessed using early wound healing scores on the first postoperative day. RESULTS: The rate of extraction space closure was faster in the experimental quadrant at all time points (T1-T4) in the PRF group and at time points (T3, T4) in the DMBM group. Comparison between experimental quadrants showed a significant increase in the rate of space closure in the PRF group T1 to T3 (P < .05). The PRF group showed higher total early healing scores than the DMBM group. CONCLUSIONS: PRF, when used in the PAOO procedure, produces a faster rate of space closure with better early wound healing than DMBM.
Authors: Carlos Fernando de Almeida Barros Mourão; Helder Valiense; Elias Rodrigues Melo; Natália Belmock Mascarenhas Freitas Mourão; Mônica Diuana-Calasans Maia Journal: Rev Col Bras Cir Date: 2015 Nov-Dec
Authors: Joseph Choukroun; Antoine Diss; Alain Simonpieri; Marie-Odile Girard; Christian Schoeffler; Steve L Dohan; Anthony J J Dohan; Jaafar Mouhyi; David M Dohan Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Date: 2006-03
Authors: Daniel Clark; Yogalakshmi Rajendran; Sarmad Paydar; Sunita Ho; Darren Cox; Mark Ryder; John Dollard; Richard T Kao Journal: J Periodontol Date: 2018-04 Impact factor: 6.993