Siobhan M Phillips1, Frank J Penedo2, Linda M Collins3, Payton Solk1, Juned Siddique1, Jing Song1, David Cella1,4, Kerry S Courneya5, Ronald T Ackermann1,6, Whitney A Welch1, Lisa A Auster-Gussman1, Madelyn Whitaker1, Erin Cullather1, Emily Izenman1, Bonnie Spring1. 1. Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois. 2. University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida. 3. New York University School of Global Public Health, New York, New York. 4. Department of Medical and Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois. 5. Faculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, Alberta, Canada. 6. Department of Medicine, General and Internal Medicine and Geriatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Abstract
BACKGROUND: The benefits of moderate to vigorous physical activity (MVPA) for breast cancer survivors are well established. However, most are insufficiently active. Fit2Thrive used the Multiphase Optimization Strategy methodology to determine the effect of 5 intervention components on MVPA in this population. METHODS: Two hundred sixty-nine participants (mean age, 52.5 years; SD, 9.9 years) received a core intervention (the Fit2Thrive self-monitoring app and Fitbit) and were randomly assigned to 5 intervention components set to on/off in a full factorial experiment: support calls, deluxe app, buddy, online gym, and text messages. The intervention was delivered over 12 weeks with a 12-week follow-up. MVPA was measured via accelerometry at the baseline (T1), at 12 weeks (T2), and at 24 weeks (T3). The main effects and interaction effects at each time point were examined for all components. RESULTS: Trial retention was high: 91.8% had valid accelerometer data at T2 or T3. Across all conditions, there were significant increases in MVPA (+53.6 min/wk; P < .001) and in the proportion of survivors meeting MVPA guidelines (+22.3%; P < .001) at T2 that were maintained but attenuated at T3 (MVPA, +24.6 min/wk; P < .001; meeting guidelines, +12.6%; P < .001). No individual components significantly improved MVPA, although increases were greater for the on level versus the off level for support calls, buddy, and text messages at T2 and T3. CONCLUSIONS: The Fit2Thrive core intervention (the self-monitoring app and Fitbit) is promising for increasing MVPA in breast cancer survivors, but the components provided no additional increases in MVPA. Future research should evaluate the core intervention in a randomized trial and determine what components optimize MVPA behaviors in breast cancer survivors.
BACKGROUND: The benefits of moderate to vigorous physical activity (MVPA) for breast cancer survivors are well established. However, most are insufficiently active. Fit2Thrive used the Multiphase Optimization Strategy methodology to determine the effect of 5 intervention components on MVPA in this population. METHODS: Two hundred sixty-nine participants (mean age, 52.5 years; SD, 9.9 years) received a core intervention (the Fit2Thrive self-monitoring app and Fitbit) and were randomly assigned to 5 intervention components set to on/off in a full factorial experiment: support calls, deluxe app, buddy, online gym, and text messages. The intervention was delivered over 12 weeks with a 12-week follow-up. MVPA was measured via accelerometry at the baseline (T1), at 12 weeks (T2), and at 24 weeks (T3). The main effects and interaction effects at each time point were examined for all components. RESULTS: Trial retention was high: 91.8% had valid accelerometer data at T2 or T3. Across all conditions, there were significant increases in MVPA (+53.6 min/wk; P < .001) and in the proportion of survivors meeting MVPA guidelines (+22.3%; P < .001) at T2 that were maintained but attenuated at T3 (MVPA, +24.6 min/wk; P < .001; meeting guidelines, +12.6%; P < .001). No individual components significantly improved MVPA, although increases were greater for the on level versus the off level for support calls, buddy, and text messages at T2 and T3. CONCLUSIONS: The Fit2Thrive core intervention (the self-monitoring app and Fitbit) is promising for increasing MVPA in breast cancer survivors, but the components provided no additional increases in MVPA. Future research should evaluate the core intervention in a randomized trial and determine what components optimize MVPA behaviors in breast cancer survivors.
Authors: Sarah J Hardcastle; Chloe Maxwell-Smith; Sviatlana Kamarova; Stephanie Lamb; Lesley Millar; Paul A Cohen Journal: Support Care Cancer Date: 2017-10-31 Impact factor: 3.603
Authors: Laura Q Rogers; Kerry S Courneya; Philip M Anton; Patricia Hopkins-Price; Steven Verhulst; Sandra K Vicari; Randall S Robbs; Robert Mocharnuk; Edward McAuley Journal: Breast Cancer Res Treat Date: 2014-11-23 Impact factor: 4.872
Authors: Whitney A Welch; Payton Solk; Lisa Auster-Gussman; Kara L Gavin; Madelyn Whitaker; Erin Cullather; Emily Izenman; Kerry S Courneya; Ronald Ackermann; Bonnie Spring; David Cella; Frank Penedo; Siobhan M Phillips Journal: Transl Behav Med Date: 2022-02-16 Impact factor: 3.626