| Literature DB >> 34812397 |
Saul Calderon-Ramirez1,2, Shengxiang Yang1, Armaghan Moemeni3, Simon Colreavy-Donnelly1, David A Elizondo1, Luis Oala4, Jorge Rodriguez-Capitan5,6, Manuel Jimenez-Navarro5,6, Ezequiel Lopez-Rubio7,6, Miguel A Molina-Cabello7,6.
Abstract
In this work we implement a COVID-19 infection detection system based on chest X-ray images with uncertainty estimation. Uncertainty estimation is vital for safe usage of computer aided diagnosis tools in medical applications. Model estimations with high uncertainty should be carefully analyzed by a trained radiologist. We aim to improve uncertainty estimations using unlabelled data through the MixMatch semi-supervised framework. We test popular uncertainty estimation approaches, comprising Softmax scores, Monte-Carlo dropout and deterministic uncertainty quantification. To compare the reliability of the uncertainty estimates, we propose the usage of the Jensen-Shannon distance between the uncertainty distributions of correct and incorrect estimations. This metric is statistically relevant, unlike most previously used metrics, which often ignore the distribution of the uncertainty estimations. Our test results show a significant improvement in uncertainty estimates when using unlabelled data. The best results are obtained with the use of the Monte Carlo dropout method. This work is licensed under a Creative Commons Attribution 4.0 License. For more information, see https://creativecommons.org/licenses/by/4.0/.Entities:
Keywords: Coronavirus; Covid-19; MixMatch; Uncertainty estimation; chest x-ray; computer aided diagnosis; semi-supervised deep learning
Year: 2021 PMID: 34812397 PMCID: PMC8545186 DOI: 10.1109/ACCESS.2021.3085418
Source DB: PubMed Journal: IEEE Access ISSN: 2169-3536 Impact factor: 3.367