Literature DB >> 34805580

Post-cholecystectomy syndrome: a retrospective study analysing the associated demographics, aetiology, and healthcare utilization.

Saad Saleem1, Simcha Weissman2, Hector Gonzalez3, Patricia Guzman Rojas4, Faisal Inayat5, Ali Alshati6, Vinaya Gaduputi7.   

Abstract

BACKGROUND: Post-cholecystectomy syndrome (PCS) is a group of heterogeneous signs and symptoms, predominately consisting of right upper quadrant abdominal pain, dyspepsia, and/or jaundice, manifesting after undergoing a cholecystectomy. According to some studies, as many as 40% of post-cholecystectomy patients are in fact, affected by this syndrome. This study aims to determine the demographics, aetiology, average length of hospital stay, and health care burden associated with PCS.
METHODS: We queried the National Inpatient Sample (NIS) database to determine inpatient admissions of PCS between 2011 and 2014 using the ICD-9 primary diagnosis code 576.0.
RESULTS: From 2011 to 2014, the number of inpatient admissions with a principal diagnosis of PCS totally 275. The average length of hospital stay was 4.28±4.28, 3.42±2.73, 3.74±1.84, and 3.79±2.78 days in 2011, 2012, 2013, and 2014, respectively. The total yearly charges were $32,079±$24,697, $27,019±$22,633, $34,898.21±$24,408, and $35,204±$32,951 in 2011, 2012, 2013, and 2014, respectively. Notably, the primary cause of PCS in our patient sample between the year 2011 and 2014, was biliary duct dysfunction, followed by Peptic ulcer disease.
CONCLUSIONS: In conclusion, there is a strong need to examine for and treat the underlying aetiology when approaching a post-cholecystectomy patient. We found that longer hospital stays, were associated with a greater health care burden, and visa versa. Furthermore, our findings help identify at-risk populations which can contribute to improving surveillance of this costly disease. 2021 Translational Gastroenterology and Hepatology. All rights reserved.

Entities:  

Keywords:  Post-cholecystectomy syndrome (PCS); biliary tract dysfunction; health care utilization; peptic ulcer disease

Year:  2021        PMID: 34805580      PMCID: PMC8573368          DOI: 10.21037/tgh.2019.11.08

Source DB:  PubMed          Journal:  Transl Gastroenterol Hepatol        ISSN: 2415-1289


  11 in total

1.  Cost variation in a laparoscopic cholecystectomy and the association with outcomes across a single health system: implications for standardization and improved resource utilization.

Authors:  David G Brauer; William G Hawkins; Steven M Strasberg; L Michael Brunt; David P Jaques; Nicholas R Mercurio; Bruce L Hall; Ryan C Fields
Journal:  HPB (Oxford)       Date:  2015-09-08       Impact factor: 3.647

2.  Imaging patients with "post-cholecystectomy syndrome": an algorithmic approach.

Authors:  O A Terhaar; S Abbas; F J Thornton; D Duke; P O'Kelly; K Abdullah; J C Varghese; M J Lee
Journal:  Clin Radiol       Date:  2005-01       Impact factor: 2.350

3.  Dynamic changes of echogenicity and the size of the papilla of Vater before and after cholecystectomy.

Authors:  M Skalicky
Journal:  J Int Med Res       Date:  2011       Impact factor: 1.671

4.  A systematic review of the aetiology and management of post cholecystectomy syndrome.

Authors:  Jennifer Isherwood; Kathryn Oakland; Achal Khanna
Journal:  Surgeon       Date:  2018-05-02       Impact factor: 2.392

5.  Cystic duct remnant after cholecystectomy: incidence studied by cholegraphy in 500 cases, and significance in 103 reoperations.

Authors:  B Bodvall; B Overgaard
Journal:  Ann Surg       Date:  1966-03       Impact factor: 12.969

6.  Laparoscopic remnant cholecystectomy and transcystic common bile duct exploration for gallbladder/cystic duct remnant with stones and choledocholithiasis after cholecystectomy.

Authors:  Jie-Gao Zhu; Zhong-Tao Zhang
Journal:  J Laparoendosc Adv Surg Tech A       Date:  2014-12-23       Impact factor: 1.878

7.  Scintigraphy versus manometry in patients with suspected biliary sphincter of Oddi dysfunction.

Authors:  A G Craig; D Peter; G T P Saccone; P Ziesing; A Wycherley; J Toouli
Journal:  Gut       Date:  2003-03       Impact factor: 23.059

Review 8.  Postcholecystectomy syndrome (PCS).

Authors:  S S Jaunoo; S Mohandas; L M Almond
Journal:  Int J Surg       Date:  2009-10-24       Impact factor: 6.071

9.  Endoscopic diagnosis and treatment of post-cholecystectomy syndrome.

Authors:  Ping-Hong Zhou; Feng-Lin Liu; Li-Qing Yao; Xin-Yu Qin
Journal:  Hepatobiliary Pancreat Dis Int       Date:  2003-02

10.  Reoperation after cholecystectomy. The role of the cystic duct stump.

Authors:  M A Rogy; R Függer; F Herbst; F Schulz
Journal:  HPB Surg       Date:  1991-06
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