Literature DB >> 34800259

An abbreviated Caprini model for VTE risk assessment in trauma.

Max D Hazeltine1, Erin M Scott2, Jon D Dorfman3.   

Abstract

The Caprini risk assessment model (RAM) is widely used to assess risk of venous thromboembolism (VTE). However, it is cumbersome with 31 variables and poses challenges with inter-rater reliability. This study aimed to determine if an abbreviated model could perform similarly in VTE risk assessment. We performed a retrospective review of trauma patients ≥ 18 years old and admitted for over 24 h at a Level I trauma center from January 1, 2018, to December 31, 2018. Demographic and clinical data were analyzed to generate Caprini scores. Using a p-value cutoff of < 0.05, the individual components of the original Caprini RAM most highly associated with VTE were identified and used to calculate an abbreviated Caprini score. Logistic regression assessed odds of inpatient VTE with the original or abbreviated Caprini RAMs. Receiver operating characteristic curves and c-statistics were generated to assess discriminatory ability. The study sample included 1279 patients. Ten risk factors were included in the abbreviated model (recent major surgery, length of surgery > 2 h, transfusion, restricted mobility > 72 h, central venous catheter, current major surgery, age, history of VTE, hip or leg fracture, and serious trauma). Compared to the original, the abbreviated model had a similar odds ratio (1.17 vs 1.07, both p-values < 0.001), c-statistic (0.747 vs 0.753), sensitivity (0.73 vs 0.76) and specificity (0.62 vs 0.61). An abbreviated Caprini RAM performs similarly to the original, may streamline workflow and allow for automation in electronic health records, potentially enhancing its use in resource limited settings.
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Caprini; Risk assessment; Thromboprophylaxis; Trauma; Venous thromboembolism

Mesh:

Year:  2021        PMID: 34800259     DOI: 10.1007/s11239-021-02611-3

Source DB:  PubMed          Journal:  J Thromb Thrombolysis        ISSN: 0929-5305            Impact factor:   2.300


  34 in total

Review 1.  Practice management guidelines for the prevention of venous thromboembolism in trauma patients: the EAST practice management guidelines work group.

Authors:  Frederick B Rogers; Mark D Cipolle; George Velmahos; Grace Rozycki; Fred A Luchette
Journal:  J Trauma       Date:  2002-07

Review 2.  Thromboprophylaxis for trauma patients.

Authors:  Luis M Barrera; Pablo Perel; Katharine Ker; Roberto Cirocchi; Eriberto Farinella; Carlos Hernando Morales Uribe
Journal:  Cochrane Database Syst Rev       Date:  2013-03-28

Review 3.  Review of the cost of venous thromboembolism.

Authors:  Maria M Fernandez; Susan Hogue; Ronald Preblick; Winghan Jacqueline Kwong
Journal:  Clinicoecon Outcomes Res       Date:  2015-08-28

4.  Validation of the Caprini Venous Thromboembolism Risk Assessment Model in Critically Ill Surgical Patients.

Authors:  Andrea T Obi; Christopher J Pannucci; Andrew Nackashi; Newaj Abdullah; Rafael Alvarez; Vinita Bahl; Thomas W Wakefield; Peter K Henke
Journal:  JAMA Surg       Date:  2015-10       Impact factor: 14.766

5.  Clinical assessment of venous thromboembolic risk in surgical patients.

Authors:  J A Caprini; J I Arcelus; J H Hasty; A C Tamhane; F Fabrega
Journal:  Semin Thromb Hemost       Date:  1991       Impact factor: 4.180

6.  Predicting venous thromboembolism in hospitalized trauma patients: a combination of the Caprini score and data-driven machine learning model.

Authors:  Lingxiao He; Lei Luo; Xiaoling Hou; Dengbin Liao; Ran Liu; Chaowei Ouyang; Guanglin Wang
Journal:  BMC Emerg Med       Date:  2021-05-10

Review 7.  Completion of the Updated Caprini Risk Assessment Model (2013 Version).

Authors:  MaryAnne Cronin; Nancy Dengler; Eugene S Krauss; Ayal Segal; Nicole Wei; Madison Daly; Frank Mota; Joseph A Caprini
Journal:  Clin Appl Thromb Hemost       Date:  2019 Jan-Dec       Impact factor: 2.389

8.  Updated guidelines to reduce venous thromboembolism in trauma patients: A Western Trauma Association critical decisions algorithm.

Authors:  Eric J Ley; Carlos V R Brown; Ernest E Moore; Jack A Sava; Kimberly Peck; David J Ciesla; Jason L Sperry; Anne G Rizzo; Nelson G Rosen; Karen J Brasel; Rosemary Kozar; Kenji Inaba; Matthew J Martin
Journal:  J Trauma Acute Care Surg       Date:  2020-11       Impact factor: 3.313

9.  Venous thromboembolism prophylaxis in the trauma intensive care unit: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document.

Authors:  Joseph F Rappold; Forest R Sheppard; Samuel P Carmichael Ii; Joseph Cuschieri; Eric Ley; Erika Rangel; Anupamaa J Seshadri; Christopher P Michetti
Journal:  Trauma Surg Acute Care Open       Date:  2021-02-24

10.  Variations in risk assessment models may contribute to the existing gap between venous thromboembolism prophylaxis guidelines and adherence.

Authors:  Deepti Vyas
Journal:  Springerplus       Date:  2012-12-11
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  1 in total

1.  A Prospective Study Evaluating Patterns of Responses to the Caprini Score to Prevent Venous Thromboembolism After Interventional Treatment for Varicose Veins.

Authors:  Marcelo Halfen Grill; Rodrigo Augusto Caffaro; Thiago Alverez Grill; Valter Castelli Júnior; Roberto Kikuchi; Camilla Moreira Ribeiro; Viviane Santana da Silva; Alfonso J Tafur; Joseph A Caprini; Eduardo Ramacciotti
Journal:  Clin Appl Thromb Hemost       Date:  2022 Jan-Dec       Impact factor: 3.512

  1 in total

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