C Noelle Driver1, Paul J Novotny2, Roberto P Benzo3. 1. Graduate School of Biomedical Sciences, School of Graduate Medical Education, Mayo Clinic, Rochester, Minnesota, United States. 2. Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States. 3. Mindful Breathing Laboratory, Department of Pulmonology and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, United States.
Abstract
INTRODUCTION: There is a knowledge gap about how much physical activity is recommended to patients with chronic obstructive pulmonary disease (COPD). We asked, what is the average difference in sedentary time and physical activity associated with clinically meaningful differences in symptoms in a large, well-characterized cohort of patients with advanced COPD? STUDY DESIGN AND METHODS: We conducted a cross-sectional analysis of daily activity data in 292 patients with stable COPD. Activity measure coefficients from multivariable linear models were used to predict the average difference in activity between patients with twice the minimal clinically important difference in reported symptoms. RESULTS: Symptoms were assessed with the Chronic Respiratory Disease Questionnaire subdomains - dyspnea, fatigue, mastery, and emotions. Daily steps, minutes in light physical activity, and sedentary time were measured by triaxial accelerometers. Average sedentary time, light physical activity, and steps were 767.6 minutes, 177.7 minutes, and 2960 steps, respectively. Individuals with 1-point better dyspnea scores averaged 24.5 (8.4-40.5) minutes less sedentary time per day. Individuals with 1-point better dyspnea and fatigue scores averaged 21.5 (10.9-32.3) minutes or 12.5 (2.0-23.2) minutes more light physical activity per day, respectively. Individuals with 1-point better dyspnea, fatigue, mastery, and emotions scores averaged 762 (546-984), 579 (351-814), 418 (207-636), and 392 (157-634) more steps per day, respectively. CONCLUSIONS: We provide guidance to clinicians counseling patients with severe COPD in activity-related goal setting on sedentary time, light physical activity, and steps associated with better symptoms. JCOPDF
INTRODUCTION: There is a knowledge gap about how much physical activity is recommended to patients with chronic obstructive pulmonary disease (COPD). We asked, what is the average difference in sedentary time and physical activity associated with clinically meaningful differences in symptoms in a large, well-characterized cohort of patients with advanced COPD? STUDY DESIGN AND METHODS: We conducted a cross-sectional analysis of daily activity data in 292 patients with stable COPD. Activity measure coefficients from multivariable linear models were used to predict the average difference in activity between patients with twice the minimal clinically important difference in reported symptoms. RESULTS: Symptoms were assessed with the Chronic Respiratory Disease Questionnaire subdomains - dyspnea, fatigue, mastery, and emotions. Daily steps, minutes in light physical activity, and sedentary time were measured by triaxial accelerometers. Average sedentary time, light physical activity, and steps were 767.6 minutes, 177.7 minutes, and 2960 steps, respectively. Individuals with 1-point better dyspnea scores averaged 24.5 (8.4-40.5) minutes less sedentary time per day. Individuals with 1-point better dyspnea and fatigue scores averaged 21.5 (10.9-32.3) minutes or 12.5 (2.0-23.2) minutes more light physical activity per day, respectively. Individuals with 1-point better dyspnea, fatigue, mastery, and emotions scores averaged 762 (546-984), 579 (351-814), 418 (207-636), and 392 (157-634) more steps per day, respectively. CONCLUSIONS: We provide guidance to clinicians counseling patients with severe COPD in activity-related goal setting on sedentary time, light physical activity, and steps associated with better symptoms. JCOPDF
Authors: Lin Yang; Chao Cao; Elizabeth D Kantor; Long H Nguyen; Xiaobin Zheng; Yikyung Park; Edward L Giovannucci; Charles E Matthews; Graham A Colditz; Yin Cao Journal: JAMA Date: 2019-04-23 Impact factor: 56.272
Authors: Robert B Banzett; Sarah H Pedersen; Richard M Schwartzstein; Robert W Lansing Journal: Am J Respir Crit Care Med Date: 2008-03-27 Impact factor: 21.405
Authors: Wolfgang Geidl; Johannes Carl; Samuel Cassar; Nicola Lehbert; Eriselda Mino; Michael Wittmann; Rupert Wagner; Konrad Schultz; Klaus Pfeifer Journal: J Clin Med Date: 2019-08-29 Impact factor: 4.241
Authors: Hans Van Remoortel; Yogini Raste; Zafeiris Louvaris; Santiago Giavedoni; Chris Burtin; Daniel Langer; Frederick Wilson; Roberto Rabinovich; Ioannis Vogiatzis; Nicholas S Hopkinson; Thierry Troosters Journal: PLoS One Date: 2012-06-20 Impact factor: 3.240
Authors: Heleen Demeyer; Chris Burtin; Miek Hornikx; Carlos Augusto Camillo; Hans Van Remoortel; Daniel Langer; Wim Janssens; Thierry Troosters Journal: PLoS One Date: 2016-04-28 Impact factor: 3.240