Literature DB >> 34779973

Angle-supported intraocular lens versus scleral-sutured posterior chamber intraocular lens in post-cataract surgery aphakic patients: two-year follow-up cost-effectiveness analysis.

Stefano Ranno1, Giovanni Mario Rabbiolo2, Stefano Lucentini2, Edoardo Ruggiero2, Saverio Vincenzo Luccarelli2, Linda Lombardi3, Paolo Nucci2,4.   

Abstract

PURPOSE: To compare visual, anatomical and economical outcomes of patients with secondary anterior chamber intraocular lens (AC-IOL) implantation and secondary scleral fixated intraocular lens (SF-IOL) implantation.
METHODS: In this retrospective observational study, 38 aphakic patients after complicated phacoemulsification divided in two groups, AC-IOL group (17 patients receiving AC-IOL implantation) and SF-IOL group (21 patients receiving SF-IOL implantation). Corrected distance visual acuity (CDVA), patient reported visual outcome (VF-14) and endothelial cell density (ECD) were measured at baseline and two-year follow-up. Complication rate was registered. The global cost of each procedure and the incremental cost-effectiveness ratio (ICER) were calculated.
RESULTS: No statistically significant difference was found in CDVA (logMAR 0.24 ± 0.17 vs. 0.32 ± 0.26, p = 0.27), VF-14 (68 ± 18 vs. 61 ± 20, p = 0.24), ECD (1456.48 ± 525.15 vs. 1341.71 ± 374.33, p = 0.48) and overall complication rate (p = 0.79) postoperatively between the SF-IOL group and the AC-IOL group. The ECD loss rate was significantly higher in the AC-IOL group (15.5% vs. 3.5%, p = 0.004). The average global cost of the two procedures was higher in the SF-IOL group (p < 0.005) and ICER showed an additional payment of 693 € for each patient in SF-IOL group against a saving of 186 endothelial cells 2 years postoperatively.
CONCLUSION: AC IOL and SF-IOL implantation showed similar outcomes in terms of visual function and safety profile. Higher ECD loss was found in AC-IOL group. The global cost of implantation was significantly lower for AC-IOL, but the ICER seems to justify the SF-IOL implantation in patients with low ECD.
© 2021. The Author(s), under exclusive licence to Springer Nature B.V.

Entities:  

Keywords:  Anterior chamber IOL; Cost-analysis; Costs; Endothelial cellular density; Scleral fixation IOL

Mesh:

Year:  2021        PMID: 34779973     DOI: 10.1007/s10792-021-02068-6

Source DB:  PubMed          Journal:  Int Ophthalmol        ISSN: 0165-5701            Impact factor:   2.031


  4 in total

1.  Translation, cultural adaptation, and Rasch analysis of the visual function (VF-14) questionnaire.

Authors:  Jyoti Khadka; Jinhai Huang; Kaziwe Mollazadegan; Rongrong Gao; Haisi Chen; Sifang Zhang; Qinmei Wang; Konrad Pesudovs
Journal:  Invest Ophthalmol Vis Sci       Date:  2014-06-10       Impact factor: 4.799

2.  Comparison of Artisan iris-claw intraocular lens implantation and posterior chamber intraocular lens sulcus fixation for aphakic eyes.

Authors:  He Teng; Hong Zhang
Journal:  Int J Ophthalmol       Date:  2014-04-18       Impact factor: 1.779

3.  Hydrogen peroxide-mediated corneal endothelial damage. Induction by oxygen free radical.

Authors:  D S Hull; K Green; L Thomas; N Alderman
Journal:  Invest Ophthalmol Vis Sci       Date:  1984-11       Impact factor: 4.799

4.  Comparison of human corneal cell density by age and corneal location: an in vivo confocal microscopy study.

Authors:  Tianyu Zheng; Qihua Le; Jiaxu Hong; Jianjiang Xu
Journal:  BMC Ophthalmol       Date:  2016-07-16       Impact factor: 2.209

  4 in total

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