Literature DB >> 34772845

Critically appraising the 2018 United Network for Organ Sharing donor allocation policy: adding life boats or rearranging the deck chairs?

Lauren K Truby1, Maryjane Farr2, Veli K Topkara3.   

Abstract

PURPOSE OF REVIEW: Due to the growing mismatch between donor supply and demand as well as unacceptably high transplant waitlist mortality, the heart organ allocation system was revised in October 2018. This review gives an overview of the changes in the new heart organ allocation system and its impact on heart transplant practice and outcomes in the United States. RECENT
FINDINGS: The 2018 heart allocation system offers a 6-tiered policy and therefore prioritizes the sickest patients on the transplant waitlist. Patients supported with temporary mechanical circulatory support devices are prioritized as Status 1 or Status 2, resulting in increased utilization of this strategy. Patients supported with durable left ventricular assist devices have been prioritized as Status 3 or 4, which has resulted in decreased utilization of this strategy. Broader geographic sharing in the new heart allocation system has resulted in prolonged donor ischemic times. Overall, the new heart allocation system has resulted in significantly lower candidate waitlist mortality, shorter waitlist times, and higher incidence of transplantation.
SUMMARY: The new United Network for Organ Sharing allocation policy confers significant advantages over the prior algorithm, allowing for decreased waitlist times and improved waitlist mortality without major impact on posttransplant survival.
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

Entities:  

Mesh:

Year:  2022        PMID: 34772845      PMCID: PMC8765708          DOI: 10.1097/ACO.0000000000001077

Source DB:  PubMed          Journal:  Curr Opin Anaesthesiol        ISSN: 0952-7907            Impact factor:   2.706


  23 in total

1.  Major advantages and critical challenge for the proposed United States heart allocation system.

Authors:  Lynne Warner Stevenson; Robert L Kormos; James B Young; James K Kirklin; Sharon A Hunt
Journal:  J Heart Lung Transplant       Date:  2016-04-16       Impact factor: 10.247

2.  An early investigation of outcomes with the new 2018 donor heart allocation system in the United States.

Authors:  Rebecca Cogswell; Ranjit John; Jerry D Estep; Sue Duval; Ryan J Tedford; Francis D Pagani; Cindy M Martin; Mandeep R Mehra
Journal:  J Heart Lung Transplant       Date:  2019-11-20       Impact factor: 10.247

3.  The future direction of the adult heart allocation system in the United States.

Authors:  D M Meyer; J G Rogers; L B Edwards; E R Callahan; S A Webber; M R Johnson; J D Vega; M J Zucker; J C Cleveland
Journal:  Am J Transplant       Date:  2015-01       Impact factor: 8.086

4.  RADIAL: a novel primary graft failure risk score in heart transplantation.

Authors:  Javier Segovia; M Dolores G Cosío; Juan M Barceló; Manuel Gómez Bueno; Pablo García Pavía; Raúl Burgos; Santiago Serrano-Fiz; Carlos García-Montero; Evaristo Castedo; Juan Ugarte; Luis Alonso-Pulpón
Journal:  J Heart Lung Transplant       Date:  2011-04-05       Impact factor: 10.247

5.  Reassessing Recipient Mortality Under the New Heart Allocation System: An Updated UNOS Registry Analysis.

Authors:  Oliver K Jawitz; Marat Fudim; Vignesh Raman; Benjamin S Bryner; Adam D DeVore; Robert J Mentz; Carmelo Milano; Chetan B Patel; Jacob N Schroder; Joseph G Rogers
Journal:  JACC Heart Fail       Date:  2020-05-14       Impact factor: 12.035

6.  Risk of severe primary graft dysfunction in patients bridged to heart transplantation with continuous-flow left ventricular assist devices.

Authors:  Lauren K Truby; Koji Takeda; Veli K Topkara; Hiroo Takayama; A Reshad Garan; Melana Yuzefpolskaya; Paolo Colombo; Yoshifumi Naka; Maryjane Farr
Journal:  J Heart Lung Transplant       Date:  2018-07-26       Impact factor: 10.247

7.  Recent Changes in Durable Left Ventricular Assist Device Bridging to Heart Transplantation.

Authors:  Amudan J Srinivasan; Laura Seese; Michael A Mathier; Gavin Hickey; Cecillia Lui; Arman Kilic
Journal:  ASAIO J       Date:  2022-02-01       Impact factor: 2.872

8.  Trends in Mechanical Support Use as a Bridge to Adult Heart Transplant Under New Allocation Rules.

Authors:  Thomas C Hanff; Michael O Harhay; Stephen E Kimmel; Maria Molina; Jeremy A Mazurek; Lee R Goldberg; Edo Y Birati
Journal:  JAMA Cardiol       Date:  2020-06-01       Impact factor: 14.676

9.  Intra-Aortic Balloon Pump Bridging to Heart Transplantation: Impact of the 2018 Allocation Change.

Authors:  Lauren V Huckaby; Laura M Seese; Michael A Mathier; Gavin W Hickey; Arman Kilic
Journal:  Circ Heart Fail       Date:  2020-08-06       Impact factor: 8.790

10.  Impact of the new heart allocation policy on patients with restrictive, hypertrophic, or congenital cardiomyopathies.

Authors:  Fouad Chouairi; Clancy W Mullan; Sounok Sen; Makoto Mori; Michael Fuery; Robert W Elder; Joshua Lesse; Kelsey Norton; Katherine A Clark; P Elliott Miller; David Mulligan; Richard Formica; Joseph G Rogers; Daniel Jacoby; Christopher Maulion; Muhammad Anwer; Arnar Geirsson; Nihar R Desai; Tariq Ahmad
Journal:  PLoS One       Date:  2021-03-02       Impact factor: 3.240

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.