Literature DB >> 25534445

The future direction of the adult heart allocation system in the United States.

D M Meyer1, J G Rogers, L B Edwards, E R Callahan, S A Webber, M R Johnson, J D Vega, M J Zucker, J C Cleveland.   

Abstract

Ensuring equitable and fair organ allocation is a central charge of the United Network for Organ Sharing (UNOS) as the Organ Procurement and Transplantation Network (OPTN) through its contract with the Department of Health and Human Services (DHHS). The OPTN/UNOS Board initiated a reassessment of the current allocation system. This paper describes the efforts of the OPTN/UNOS Heart Subcommittee, acting on behalf of the OPTN/UNOS Thoracic Organ Transplantation Committee, to modify the current allocation system. The Subcommittee assessed the limitations of the current three-tiered system, outcomes of patients with status exceptions, emerging ventricular assist device (VAD) population, options for improved geographic sharing and status of potentially disenfranchised groups. They analyzed waiting list and posttransplant mortality rates of a contemporary cohort of patient groups at risk, in collaboration with the Scientific Registry of Transplant Recipients to develop a proposed multi-tiered allocation scheme. This proposal provides a framework for simulation modeling to project whether candidates would have better waitlist survival in the revised allocation system, and whether posttransplant survival would remain stable. The tiers are subject to change, based on further analysis by the Heart Subcommittee and will lead to the development of a more effective and equitable heart allocation system. © Copyright 2014 The American Society of Transplantation and the American Society of Transplant Surgeons.

Entities:  

Keywords:  United Network for Organ Sharing (UNOS); ethics and public policy; heart transplantation/cardiology; organ allocation; organ procurement and allocation

Mesh:

Year:  2015        PMID: 25534445     DOI: 10.1111/ajt.13030

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  25 in total

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Review 2.  Frailty in the End-Stage Lung Disease or Heart Failure Patient: Implications for the Perioperative Transplant Clinician.

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Review 4.  Emerging science in paediatric heart transplantation: donor allocation, biomarkers, and the quest for evidence-based medicine.

Authors:  Kevin P Daly
Journal:  Cardiol Young       Date:  2015-08       Impact factor: 1.093

5.  Does Survival on the Heart Transplant Waiting List Depend on the Underlying Heart Disease?

Authors:  Eileen M Hsich; Joseph G Rogers; Dennis M McNamara; David O Taylor; Randall C Starling; Eugene H Blackstone; Jesse D Schold
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6.  Mechanical Circulatory Support Device Utilization and Heart Transplant Waitlist Outcomes in Patients With Restrictive and Hypertrophic Cardiomyopathy.

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Review 7.  Heart transplantation for adults with congenital heart disease: current status and future prospects.

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8.  The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult heart transplantation report - 2019; focus theme: Donor and recipient size match.

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Journal:  J Heart Lung Transplant       Date:  2019-08-10       Impact factor: 10.247

9.  Great variability in donor heart acceptance practices across the United States.

Authors:  Kiran K Khush; Robyn L Ball
Journal:  Am J Transplant       Date:  2020-01-20       Impact factor: 8.086

10.  Reassessing Recipient Mortality Under the New Heart Allocation System: An Updated UNOS Registry Analysis.

Authors:  Oliver K Jawitz; Marat Fudim; Vignesh Raman; Benjamin S Bryner; Adam D DeVore; Robert J Mentz; Carmelo Milano; Chetan B Patel; Jacob N Schroder; Joseph G Rogers
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