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Literature DB >> 3476962

Site-directed serology with synthetic peptides representing the large glycoprotein G of respiratory syncytial virus.

E Norrby, M A Mufson, H Alexander, R A Houghten, R A Lerner.

Abstract

A set of 23 nested 15-amino-acid-long peptides with overlaps of 5 amino acids, representing the complete extramembranous part of the large glycoprotein G of respiratory syncytial (RS) virus, was analyzed in ELISA against different sera containing virus-specific antibodies. Seven of the peptides reacted with rabbit hyperimmune sera against purified virions. In contrast, only one of these seven peptides reacted with murine monoclonal antibodies specific for G. In connection with RS virus infections in humans, increase of antibody titers against three peptides was found in about one-third of the cases. These three peptides were included among those identified by both murine and rabbit antibodies. The present findings may open possibilities for site-directed clinical serology in the case of RS virus infections.

Entities: Disease Species

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Year: 1987 PMID： 3476962 PMCID： PMC299121 DOI： 10.1073/pnas.84.18.6572

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

25 in total

1. Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine.

Authors: H W Kim; J G Canchola; C D Brandt; G Pyles; R M Chanock; K Jensen; R H Parrott
Journal: Am J Epidemiol Date: 1969-04 Impact factor: 4.897

2. An epidemiologic study of altered clinical reactivity to respiratory syncytial (RS) virus infection in children previously vaccinated with an inactivated RS virus vaccine.

Authors: A Z Kapikian; R H Mitchell; R M Chanock; R A Shvedoff; C E Stewart
Journal: Am J Epidemiol Date: 1969-04 Impact factor: 4.897

3. Tapping the immunological repertoire to produce antibodies of predetermined specificity.

Authors: R A Lerner
Journal: Nature Date: 1982-10-14 Impact factor: 49.962

4. The effects of monoclonal antibodies on biologic activities of structural proteins of Sendai virus.

Authors: C Orvell; M Grandien
Journal: J Immunol Date: 1982-12 Impact factor: 5.422

5. Protection from respiratory syncytial virus infection in cotton rats by passive transfer of monoclonal antibodies.

Authors: E E Walsh; J J Schlesinger; M W Brandriss
Journal: Infect Immun Date: 1984-02 Impact factor: 3.441

6. Classification of hybridomas to respiratory syncytial virus glycoproteins.

Authors: B F Fernie; P J Cote; J L Gerin
Journal: Proc Soc Exp Biol Med Date: 1982-12

7. Immunochemical identification of viral and nonviral proteins of the respiratory syncytial virus virion.

Authors: B F Fernie; J L Gerin
Journal: Infect Immun Date: 1982-07 Impact factor: 3.441

Review 8. Immunopathologic mechanisms in lower respiratory tract disease of infants due to respiratory syncytial virus.

Authors: K McIntosh; J M Fishaut
Journal: Prog Med Virol Date: 1980

9. Immunological relationships between homologous structural polypeptides of measles and canine distemper virus.

Authors: C Orvell; E Norrby
Journal: J Gen Virol Date: 1980-10 Impact factor: 3.891

10. Risk of respiratory syncytial virus infection for infants from low-income families in relationship to age, sex, ethnic group, and maternal antibody level.

Authors: W P Glezen; A Paredes; J E Allison; L H Taber; A L Frank
Journal: J Pediatr Date: 1981-05 Impact factor: 4.406

30 in total

1. Structural analysis of the carboxy terminus of bacteriophage lambda repressor determined by antipeptide antibodies.

Authors: R Sussman; H B Alexander
Journal: J Bacteriol Date: 1989-03 Impact factor: 3.490

2. Human cytomegalovirus structural proteins: immune reaction against pp150 synthetic peptides.

Authors: M P Landini; A Ripalti; K Sra; P Pouletty
Journal: J Clin Microbiol Date: 1991-09 Impact factor: 5.948

3. Epstein-Barr virus nuclear antigen 1 linear epitopes that are reactive with immunoglobulin A (IgA) or IgG in sera from nasopharyngeal carcinoma patients or from healthy donors.

Authors: H M Cheng; Y T Foong; C K Sam; U Prasad; J Dillner
Journal: J Clin Microbiol Date: 1991-10 Impact factor: 5.948

Review 4. Respiratory syncytial virus genetic and antigenic diversity.

Authors: W M Sullender
Journal: Clin Microbiol Rev Date: 2000-01 Impact factor: 26.132

5. A subtype-specific peptide-based enzyme immunoassay for detection of antibodies to the G protein of human respiratory syncytial virus is more sensitive than routine serological tests.

Authors: J P Langedijk; A H Brandenburg; W G Middel; A Osterhaus; R H Meloen; J T van Oirschot
Journal: J Clin Microbiol Date: 1997-07 Impact factor: 5.948

6. Linear epitopes of the replication-activator protein of Epstein-Barr virus recognised by specific serum IgG in nasopharyngeal carcinoma.

Authors: H M Cheng; Y T Foong; A J AbuSamah; J Dillner; C K Sam; U Prasad
Journal: Cancer Immunol Immunother Date: 1995-04 Impact factor: 6.968

7. Multiplex assay for detection of strain-specific antibodies against the two variable regions of the G protein of respiratory syncytial virus.

Authors: Les P Jones; Hao-Qiang Zheng; Ruth A Karron; Teresa C T Peret; Cecelia Tsou; Larry J Anderson
Journal: Clin Diagn Lab Immunol Date: 2002-05

8. Identification of multiple protective epitopes (protectopes) in the central conserved domain of a prototype human respiratory syncytial virus G protein.

Authors: H Plotnicky-Gilquin; L Goetsch; T Huss; T Champion; A Beck; J F Haeuw; T N Nguyen; J Y Bonnefoy; N Corvaïa; U F Power
Journal: J Virol Date: 1999-07 Impact factor: 5.103

9. Evolution of subgroup A respiratory syncytial virus: evidence for progressive accumulation of amino acid changes in the attachment protein.

Authors: P A Cane; C R Pringle
Journal: J Virol Date: 1995-05 Impact factor: 5.103

10. Characterization of B cell epitopes on the 16K antigen of Mycobacterium tuberculosis.

Authors: A Verbon; R A Hartskeerl; C Moreno; A H Kolk
Journal: Clin Exp Immunol Date: 1992-09 Impact factor: 4.330