Literature DB >> 6363300

Protection from respiratory syncytial virus infection in cotton rats by passive transfer of monoclonal antibodies.

E E Walsh, J J Schlesinger, M W Brandriss.   

Abstract

The effects of passive administration of neutralizing monoclonal antibodies (MAB) to respiratory syncytial virus glycoproteins (GP90 and VP70) was evaluated in cotton rats challenged with respiratory syncytial virus. Animals injected with MAB to VP70 had lower mean viral titers in lung tissues than did controls (log10 2.5 versus 5.4 PFU/g; P less than 0.001), as did cotton rats given MAB to GP90 (log10 2.1 versus 5.0 PFU/g; P less than 0.001). Fifty percent of animals given either MAB had no detectable virus in lung tissues, whereas virus was detected in the lungs of all controls. Virus growth in nasal turbinates was decreased but not eliminated in recipients of either MAB.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6363300      PMCID： PMC264366          DOI： 10.1128/iai.43.2.756-758.1984

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  13 in total

1.  Epidemiology of respiratory syncytial virus infection in Washington, D.C. II. Infection and disease with respect to age, immunologic status, race and sex.

Authors:  R H Parrott; H W Kim; J O Arrobio; D S Hodes; B R Murphy; C D Brandt; E Camargo; R M Chanock
Journal:  Am J Epidemiol       Date:  1973-10       Impact factor: 4.897

2.  Respiratory syncytial virus polypeptides: their location in the virion.

Authors:  M Peeples; S Levine
Journal:  Virology       Date:  1979-05       Impact factor: 3.616

3.  Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine.

Authors:  H W Kim; J G Canchola; C D Brandt; G Pyles; R M Chanock; K Jensen; R H Parrott
Journal:  Am J Epidemiol       Date:  1969-04       Impact factor: 4.897

4.  Experimental respiratory syncytial virus infection of adults. Possible mechanisms of resistance to infection and illness.

Authors:  J Mills; J E Van Kirk; P F Wright; R M Chanock
Journal:  J Immunol       Date:  1971-07       Impact factor: 5.422

5.  Monoclonal antibodies to respiratory syncytial virus proteins: identification of the fusion protein.

Authors:  E E Walsh; J Hruska
Journal:  J Virol       Date:  1983-07       Impact factor: 5.103

Review 6.  The role of viral glycoproteins in adsorption, penetration, and pathogenicity of viruses.

Authors:  P W Choppin; A Scheid
Journal:  Rev Infect Dis       Date:  1980 Jan-Feb

7.  Differences in the appearance of antibodies to structural components of measles virus after immunization with inactivated and live virus.

Authors:  E Norrby; G Enders-Ruckle; V Meulen
Journal:  J Infect Dis       Date:  1975-09       Impact factor: 5.226

8.  Role of maternal antibody in pneumonia and bronchiolitis due to respiratory syncytial virus.

Authors:  C L Lamprecht; H E Krause; M A Mufson
Journal:  J Infect Dis       Date:  1976-09       Impact factor: 5.226

Review 9.  Importance of antibodies to the fusion glycoprotein of paramyxoviruses in the prevention of spread of infection.

Authors:  D C Merz; A Scheid; P W Choppin
Journal:  J Exp Med       Date:  1980-02-01       Impact factor: 14.307

10.  Antigenic drift in influenza A viruses. I. Selection and characterization of antigenic variants of A/PR/8/34 (HON1) influenza virus with monoclonal antibodies.

Authors:  W Gerhard; R G Webster
Journal:  J Exp Med       Date:  1978-08-01       Impact factor: 14.307
View more
  62 in total

1.  Safety and pharmacokinetics of an intramuscular monoclonal antibody (SB 209763) against respiratory syncytial virus (RSV) in infants and young children at risk for severe RSV disease.

Authors:  H C Meissner; J R Groothuis; W J Rodriguez; R C Welliver; G Hogg; P H Gray; R Loh; E A Simoes; P Sly; A K Miller; A I Nichols; D K Jorkasky; D E Everitt; K A Thompson
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

2.  Neutralization of human respiratory syncytial virus infectivity by antibodies and low-molecular-weight compounds targeted against the fusion glycoprotein.

Authors:  Margarita Magro; David Andreu; Paulino Gómez-Puertas; José A Melero; Concepción Palomo
Journal:  J Virol       Date:  2010-06-09       Impact factor: 5.103

Review 3.  The respiratory syncitial virus and its role in acute bronchiolitis.

Authors:  M L Everard; A D Milner
Journal:  Eur J Pediatr       Date:  1992-09       Impact factor: 3.183

4.  Premature stop codons in the G glycoprotein of human respiratory syncytial viruses resistant to neutralization by monoclonal antibodies.

Authors:  P Rueda; T Delgado; A Portela; J A Melero; B García-Barreno
Journal:  J Virol       Date:  1991-06       Impact factor: 5.103

5.  Expression of the F and HN glycoproteins of human parainfluenza virus type 3 by recombinant vaccinia viruses: contributions of the individual proteins to host immunity.

Authors:  M K Spriggs; B R Murphy; G A Prince; R A Olmsted; P L Collins
Journal:  J Virol       Date:  1987-11       Impact factor: 5.103

6.  The role of maternal antibodies in the emergence of severe disease as a result of fragmentation.

Authors:  David Fouchet; Stéphane Marchandeau; Nargès Bahi-Jaber; Dominique Pontier
Journal:  J R Soc Interface       Date:  2007-06-22       Impact factor: 4.118

7.  Passive protection against rotavirus-induced diarrhea by monoclonal antibodies to surface proteins vp3 and vp7.

Authors:  P A Offit; R D Shaw; H B Greenberg
Journal:  J Virol       Date:  1986-05       Impact factor: 5.103

8.  Amino acid variation within the fusion protein of respiratory syncytial virus subtype A and B strains during annual epidemics in South Africa.

Authors:  Elizabeth Agenbach; Caroline T Tiemessen; Marietjie Venter
Journal:  Virus Genes       Date:  2005-03       Impact factor: 2.332

9.  Antigenic analysis of the F protein of the bovine respiratory syncytial virus: identification of two distinct antigenic sites involved in fusion inhibition.

Authors:  J P Matheise; K Walravens; A Collard; P Coppe; J J Letesson
Journal:  Arch Virol       Date:  1995       Impact factor: 2.574

10.  Expression of the F glycoprotein of respiratory syncytial virus by a recombinant vaccinia virus: comparison of the individual contributions of the F and G glycoproteins to host immunity.

Authors:  R A Olmsted; N Elango; G A Prince; B R Murphy; P R Johnson; B Moss; R M Chanock; P L Collins
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.