Literature DB >> 34761681

Preferences of adults with cancer for systemic cancer treatment: do preferences differ based on age?

Prajwal Dhakal1, Christopher S Wichman2, Bunny Pozehl3, Meaghann Weaver4,5, Alfred L Fisher6, Julie Vose7,8, R Gregory Bociek7,8, Vijaya R Bhatt7,8.   

Abstract

Background: We used the Therapy Preference Scale, a 30-item questionnaire, to determine cancer treatment preferences of adults with cancer.
Methods: We used Wilcoxon's rank sum test and Fisher's exact test to compare the preferences of younger (<60 years) versus older adults (≥60 years).
Results: While 56% of patients would accept treatment offering increased life expectancy at an expense of short-term side effects, 75% preferred maintenance of cognition, functional ability and quality of life to quantity of days. Oral instead of intravenous treatment (p = 0.003), shorter hospital stay (p = 0.03), preservation of cognitive function (p = 0.01) and avoidance of pain (p = 0.02) were more important to older patients compared with younger patients.
Conclusion: Many patients prioritized maintenance of cognition, functional ability and quality of life; older patients valued oral treatment, shorter hospital stay, preservation of cognitive function and avoidance of pain.

Entities:  

Keywords:  cancer; cognition; life expectancy; patients; preferences; quality of life; questionnaire; therapy; treatment

Mesh:

Substances:

Year:  2021        PMID: 34761681      PMCID: PMC8819600          DOI: 10.2217/fon-2021-0260

Source DB:  PubMed          Journal:  Future Oncol        ISSN: 1479-6694            Impact factor:   3.674


  33 in total

1.  Probability tables for individual comparisons by ranking methods.

Authors:  F WILCOXIN
Journal:  Biometrics       Date:  1947-09       Impact factor: 2.571

2.  Preference weights for chemotherapy side effects from the perspective of women with breast cancer.

Authors:  I Kuchuk; N Bouganim; K Beusterien; J Grinspan; L Vandermeer; S Gertler; S F Dent; X Song; R Segal; S Mazzarello; F Crawley; G Dranitsaris; M Clemons
Journal:  Breast Cancer Res Treat       Date:  2013-10-16       Impact factor: 4.872

3.  Treatment patterns and outcomes of octogenarian patients with acute myeloid leukemia.

Authors:  Vijaya R Bhatt; Valerie Shostrom; James O Armitage; Krishna Gundabolu
Journal:  Am J Hematol       Date:  2019-04-01       Impact factor: 10.047

4.  Patients' and doctors' preferences for adjuvant chemotherapy in resected non-small-cell lung cancer: What makes it worthwhile?

Authors:  Prunella Blinman; Brett Hughes; Catherine Crombie; Tim Christmas; Malcolm Hudson; Anne-Sophie Veillard; Nick Muljadi; Michael Millward; Gavin Wright; Peter Flynn; Morgan Windsor; Martin Stockler; Sue-Anne McLachlan
Journal:  Eur J Cancer       Date:  2015-06-06       Impact factor: 9.162

5.  The financial toxicity of cancer treatment: a pilot study assessing out-of-pocket expenses and the insured cancer patient's experience.

Authors:  S Yousuf Zafar; Jeffrey M Peppercorn; Deborah Schrag; Donald H Taylor; Amy M Goetzinger; Xiaoyin Zhong; Amy P Abernethy
Journal:  Oncologist       Date:  2013-02-26

6.  Cost sharing and adherence to tyrosine kinase inhibitors for patients with chronic myeloid leukemia.

Authors:  Stacie B Dusetzina; Aaron N Winn; Gregory A Abel; Haiden A Huskamp; Nancy L Keating
Journal:  J Clin Oncol       Date:  2013-12-23       Impact factor: 44.544

7.  Physicians' propensity to discuss prognosis is associated with patients' awareness of prognosis for metastatic cancers.

Authors:  Pang-Hsiang Liu; Mary Beth Landrum; Jane C Weeks; Haiden A Huskamp; Katherine L Kahn; Yulei He; Jennifer W Mack; Nancy L Keating
Journal:  J Palliat Med       Date:  2014-04-17       Impact factor: 2.947

8.  A Prospective Comparison of Younger and Older Patients' Preferences for Adjuvant Chemotherapy and Hormonal Therapy in Early Breast Cancer.

Authors:  Victoria C Hamelinck; Esther Bastiaannet; Arwen H Pieterse; Nienke A de Glas; Johanneke E A Portielje; Jos W S Merkus; Irma D M den Hoed; Cornelis J H van de Velde; Gerrit-Jan Liefers; Anne M Stiggelbout
Journal:  Clin Breast Cancer       Date:  2016-04-21       Impact factor: 3.225

Review 9.  Patient-reported preferences for oral versus intravenous administration for the treatment of cancer: a review of the literature.

Authors:  Daniel Eek; Meaghan Krohe; Iyar Mazar; Alison Horsfield; Farrah Pompilus; Rachel Friebe; Alan L Shields
Journal:  Patient Prefer Adherence       Date:  2016-08-24       Impact factor: 2.711

10.  Addressing Patients' Priorities as a Strategy to Improve Value.

Authors:  Yu-Ning Wong; Nancy Roach; Neal J Meropol
Journal:  Oncologist       Date:  2016-10-14
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  4 in total

Review 1.  Precision Medicine in Myeloid Malignancies: Hype or Hope?

Authors:  Shristi Upadhyay Banskota; Nabin Khanal; Rosalyn I Marar; Prajwal Dhakal; Vijaya Raj Bhatt
Journal:  Curr Hematol Malig Rep       Date:  2022-08-16       Impact factor: 4.213

Review 2.  Patient Preferences for Treatment Outcomes in Oncology with a Focus on the Older Patient-A Systematic Review.

Authors:  Petronella A L Nelleke Seghers; Anke Wiersma; Suzanne Festen; Mariken E Stegmann; Pierre Soubeyran; Siri Rostoft; Shane O'Hanlon; Johanneke E A Portielje; Marije E Hamaker
Journal:  Cancers (Basel)       Date:  2022-02-23       Impact factor: 6.639

3.  What Defines Quality of Life for Older Patients Diagnosed with Cancer? A Qualitative Study.

Authors:  Petronella A L Nelleke Seghers; Jolina A Kregting; Lieke H van Huis-Tanja; Pierre Soubeyran; Shane O'Hanlon; Siri Rostoft; Marije E Hamaker; Johanneke E A Portielje
Journal:  Cancers (Basel)       Date:  2022-02-22       Impact factor: 6.639

4.  Multi-Disciplinary Care Planning of Ovarian Cancer in Older Patients: General Statement-A Position Paper from SOFOG-GINECO-FRANCOGYN-SFPO.

Authors:  Leila Bengrine; Naoual Bakrin; Frédérique Rousseau; Vincent Lavoué; Claire Falandry
Journal:  Cancers (Basel)       Date:  2022-03-02       Impact factor: 6.639

  4 in total

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