| Literature DB >> 34751403 |
Benjamin D Lee1,2, Uri Neri3, Caleb J Oh4, Peter Simmonds2, Eugene V Koonin1.
Abstract
We introduce ViroidDB, a value-added database that attempts to collect all known viroid and viroid-like circular RNA sequences into a single resource. Spanning about 10 000 unique sequences, ViroidDB includes viroids, retroviroid-like elements, small circular satellite RNAs, ribozyviruses, and retrozymes. Each sequence's secondary structure, ribozyme content, and cluster membership are predicted via a custom pipeline optimized for handling circular RNAs. The data can be explored via a purpose-built user interface that features visualizations, multiple sequence alignments, and a portal for downloading bulk data. Users can browse the data by sequence type, taxon, or typo-tolerant search of metadata fields. The database is freely accessible at https://viroids.org. Published by Oxford University Press on behalf of Nucleic Acids Research 2021.Entities:
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Year: 2022 PMID: 34751403 PMCID: PMC8728161 DOI: 10.1093/nar/gkab974
Source DB: PubMed Journal: Nucleic Acids Res ISSN: 0305-1048 Impact factor: 16.971