| Literature DB >> 34731433 |
Xi-Bin Zhou1, Yu-Xing Zhang1, Chun-Xiang Zhou1,2, Jun-Jie Ma3.
Abstract
Due to its complex pathogenesis and lack of effective therapeutic methods, Alzheimer's disease (AD) has become a severe public health problem worldwide. Recent studies have discovered the function of central nervous system lymphatic drainage, which provides a new strategy for the treatment of AD. Chinese herbal medicine (CHM) has been considered as a cure for AD for hundreds of years in China, and its effect on scavenging β-amyloid protein in the brain of AD patients has been confirmed. In this review, the mechanism of central nervous system lymphatic drainage and the regulatory functions of CHM on correlation factors were briefly summarized. The advances in our understanding regarding the treatment of AD via regulating the central lymphatic system with CHM will promote the clinical application of CHM in AD patients and the discovery of new therapeutic drugs.Entities:
Keywords: Alzheimer’s disease; Chinese herbal medicine; central lymphatic system
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Year: 2021 PMID： 34731433 DOI： 10.1007/s11655-021-3342-5
Source DB: PubMed Journal: Chin J Integr Med ISSN： 1672-0415 Impact factor: 1.978