PURPOSE: Although a central venous catheter (CVC) is often needed perioperatively for intraoperative and nutritional management of esophageal cancer (EC), the catheter placement impacts the risk of venous thrombosis. We examined the risks of thrombus formation by catheter type, placement, and duration. METHODS: In total, 226 patients with EC were enrolled in this retrospective study. Patients were classified into one of three groups: those with a conventional CVC (cCVC), a peripherally inserted central catheter (PICC), or an antithrombogenic agent-coated PICC (secPICC). The thrombus formation and clinicopathological features were examined. RESULTS: The frequency of all types of thrombosis was significantly lower in the secPICC group (p < 0.01). Although deep vein thrombosis was frequent in the cCVC group, catheter thrombosis was frequent in the PICC group. In a univariate analysis in patients with the PICC and secPICC groups, less thrombus formation was observed in the secPICC (p = 0.01), short placement time (p = 0.02), and right-sided placement (p < 0.01). Furthermore, a multivariate analysis revealed that secPICC (p = 0.049) and right-sided placement (p = 0.04) significantly reduced rates of thrombus formation. CONCLUSION: In patients with EC, secPICC and right-sided placement reduce perioperative venous thrombus formation.
PURPOSE: Although a central venous catheter (CVC) is often needed perioperatively for intraoperative and nutritional management of esophageal cancer (EC), the catheter placement impacts the risk of venous thrombosis. We examined the risks of thrombus formation by catheter type, placement, and duration. METHODS: In total, 226 patients with EC were enrolled in this retrospective study. Patients were classified into one of three groups: those with a conventional CVC (cCVC), a peripherally inserted central catheter (PICC), or an antithrombogenic agent-coated PICC (secPICC). The thrombus formation and clinicopathological features were examined. RESULTS: The frequency of all types of thrombosis was significantly lower in the secPICC group (p < 0.01). Although deep vein thrombosis was frequent in the cCVC group, catheter thrombosis was frequent in the PICC group. In a univariate analysis in patients with the PICC and secPICC groups, less thrombus formation was observed in the secPICC (p = 0.01), short placement time (p = 0.02), and right-sided placement (p < 0.01). Furthermore, a multivariate analysis revealed that secPICC (p = 0.049) and right-sided placement (p = 0.04) significantly reduced rates of thrombus formation. CONCLUSION: In patients with EC, secPICC and right-sided placement reduce perioperative venous thrombus formation.
Authors: M Nakamura; H Fujioka; N Yamada; M Sakuma; O Okada; N Nakanishi; Y Miyahara; T Kuriyama; T Kunieda; T Sugimoto; T Nakano Journal: Clin Cardiol Date: 2001-02 Impact factor: 2.882
Authors: Manuela Bonizzoli; Stefano Batacchi; Giovanni Cianchi; Giovanni Zagli; Francesco Lapi; Valentina Tucci; Giacomo Martini; Simona Di Valvasone; Adriano Peris Journal: Intensive Care Med Date: 2010-09-21 Impact factor: 17.440
Authors: Vineet Chopra; Sarah Anand; Andy Hickner; Michael Buist; Mary Am Rogers; Sanjay Saint; Scott A Flanders Journal: Lancet Date: 2013-05-20 Impact factor: 79.321