Literature DB >> 34722723

A Novel Hybrid Stent with Endoscopic Vacuum Therapy for Treating Leaks of the Upper Gastrointestinal Tract.

Seung-Hun Chon1, Ulrich Töx2, Florian Lorenz2, Isabel Rieck2, Britta Janina Wagner3, Robert Kleinert1, Hans Friedrich Fuchs1, Tobias Goeser2, Alexander Quaas3, Christiane J Bruns1.   

Abstract

INTRODUCTION: Self-expanding metal stents (SEMS) are an established option for treating leaks in the upper gastrointestinal tract, and endoscopic vacuum therapy (EVT) has become a promising alternative. A novel approach is the use of an esophageal hybrid SEMS (VACStent®), which can maintain esophageal passage during EVT. We present the first study demonstrating successful use of the VACStent® for treating leaks of the upper gastrointestinal tract.
METHOD: We performed a retrospective, single-center study of all patients who underwent endoscopic stenting with the VACStent® of leaks in the upper gastrointestinal tract.
RESULTS: Indications for treatment with the VACStent® were: iatrogenic esophageal perforation (n = 1), spontaneous perforation (n = 2), esophageal fistula (n = 2), and anastomotic leak after upper gastrointestinal surgery (n = 5). Successful application of the VACStent® was achieved in all patients (n = 10; 100%) with a total of 15 interventions. VACStent® therapy was used as a first-line treatment in 5 patient (success rate 80%; 4 out 5 patients) and as a second-line treatment after failed previous endoscopic therapy in 5 patients (success rate 60%; 3 out of 5 patients). Overall, VACStent® treatment was successful in 70% of the patients (7 out of 10). No severe VACStent® treatment-related adverse events occurred.
CONCLUSION: The initial experience has been that the technical application of the VACStent® is safe and technically feasible. However, due to the small number of patients this study could not show the clear advantages of this novel hybrid stent. More studies are necessary to show significant advantages.
Copyright © 2020 by S. Karger AG, Basel.

Entities:  

Keywords:  Anastomotic leak; Endoscopic vacuum therapy; Esophageal perforation; Self-expanding metal stent

Year:  2020        PMID: 34722723      PMCID: PMC8543322          DOI: 10.1159/000512320

Source DB:  PubMed          Journal:  Visc Med        ISSN: 2297-4725


  20 in total

Review 1.  Expandable metal stents for the treatment of cancerous obstruction of the gastrointestinal tract.

Authors:  T H Baron
Journal:  N Engl J Med       Date:  2001-05-31       Impact factor: 91.245

Review 2.  Anastomotic Leakage after Upper Gastrointestinal Surgery: Endoscopic Treatment.

Authors:  Georg Kähler
Journal:  Visc Med       Date:  2017-06-14

Review 3.  The role of esophageal stents in the management of esophageal anastomotic leaks and benign esophageal perforations.

Authors:  Bobby V M Dasari; David Neely; Andrew Kennedy; Gary Spence; Paul Rice; Eamon Mackle; Emmanuel Epanomeritakis
Journal:  Ann Surg       Date:  2014-05       Impact factor: 12.969

4.  Successful closure of defects in the upper gastrointestinal tract by endoscopic vacuum therapy (EVT): a prospective cohort study.

Authors:  Mike G Laukoetter; Rudolf Mennigen; Philipp A Neumann; Sameer Dhayat; Gabriele Horst; Daniel Palmes; Norbert Senninger; Thorsten Vowinkel
Journal:  Surg Endosc       Date:  2016-10-05       Impact factor: 4.584

5.  VACStent: a new option for endoscopic vacuum therapy in patients with esophageal anastomotic leaks after upper gastrointestinal surgery.

Authors:  Seung-Hun Chon; Isabel Bartella; Martin Bürger; Isabel Rieck; Tobias Goeser; Wolfgang Schröder; Christiane Josephine Bruns
Journal:  Endoscopy       Date:  2019-12-02       Impact factor: 10.093

6.  Endoscopic vacuum therapy versus stenting for postoperative esophago-enteric anastomotic leakage: systematic review and meta-analysis.

Authors:  Pasquale Scognamiglio; Matthias Reeh; Karl Karstens; Eugen Bellon; Marcus Kantowski; Gerhard Schön; Antonia Zapf; Seung-Hun Chon; Jakob R Izbicki; Michael Tachezy
Journal:  Endoscopy       Date:  2020-04-21       Impact factor: 10.093

7.  Intrathoracic anastomotic leakage and mortality after esophageal cancer resection: a population-based study.

Authors:  Martin Rutegård; Pernilla Lagergren; Ioannis Rouvelas; Jesper Lagergren
Journal:  Ann Surg Oncol       Date:  2011-07-19       Impact factor: 5.344

Review 8.  Diagnosis and management of iatrogenic endoscopic perforations: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement.

Authors:  Gregorios A Paspatis; Jean-Marc Dumonceau; Marc Barthet; Søren Meisner; Alessandro Repici; Brian P Saunders; Antonios Vezakis; Jean Michel Gonzalez; Stine Ydegaard Turino; Zacharias P Tsiamoulos; Paul Fockens; Cesare Hassan
Journal:  Endoscopy       Date:  2014-07-21       Impact factor: 10.093

9.  Results of endoscopic vacuum-assisted closure device for treatment of upper GI leaks.

Authors:  Marc Bludau; Hans F Fuchs; Till Herbold; Martin K H Maus; Hakan Alakus; Felix Popp; Jessica M Leers; Christiane J Bruns; Arnulf H Hölscher; Wolfgang Schröder; Seung-Hun Chon
Journal:  Surg Endosc       Date:  2017-12-07       Impact factor: 4.584

10.  Outcome of Self-Expanding Metal Stents in the Treatment of Anastomotic Leaks After Ivor Lewis Esophagectomy.

Authors:  Patrick Sven Plum; Till Herbold; Felix Berlth; Hildegard Christ; Hakan Alakus; Marc Bludau; De-Hua Chang; Christiane Josephine Bruns; Arnulf Heinrich Hölscher; Seung-Hun Chon
Journal:  World J Surg       Date:  2019-03       Impact factor: 3.352

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  2 in total

1.  Management of intra-thoracic anastomotic leakages after esophagectomy: updated systematic review and meta-analysis of endoscopic vacuum therapy versus stenting.

Authors:  Pasquale Scognamiglio; Matthias Reeh; Nathaniel Melling; Marcus Kantowski; Ann-Kathrin Eichelmann; Seung-Hun Chon; Nader El-Sourani; Gerhard Schön; Alexandra Höller; Jakob R Izbicki; Michael Tachezy
Journal:  BMC Surg       Date:  2022-08-11       Impact factor: 2.030

Review 2.  Endoscopic vacuum therapy in the upper gastrointestinal tract: when and how to use it.

Authors:  Christian A Gutschow; Christoph Schlag; Diana Vetter
Journal:  Langenbecks Arch Surg       Date:  2022-01-18       Impact factor: 2.895

  2 in total

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