| Literature DB >> 34697664 |
Abstract
Immunosuppression is complex, fraught with on-target and off-target adverse effects, and hard to get right but is the key to successful allotransplantation. Herein, we review the key immunosuppressive agent classes used for kidney transplant, highlighting mechanisms of action and typical clinical use.Entities:
Keywords: Antibody mediation rejection; Calcineurin inhibitors; Immunosuppression; Induction therapy; Kidney transplantation; Rejection; T-cell depleting agents; Transplant protocols
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Year: 2022 PMID: 34697664 DOI: 10.1007/164_2021_546
Source DB: PubMed Journal: Handb Exp Pharmacol ISSN: 0171-2004