Dirk Rades1, Svenja Kopelke2,3, Soeren Tvilsted4, Troels W Kjaer5, Steven E Schild6, Tobias Bartscht3. 1. Department of Radiation Oncology, University of Lübeck, Lübeck, Germany; dirk.rades@uksh.de. 2. Department of Radiation Oncology, University of Lübeck, Lübeck, Germany. 3. Department of Hematology and Oncology, University of Lübeck, Lübeck, Germany. 4. Research Projects and Clinical Optimization, Zealand University Hospital, Koege, Denmark. 5. Neurological Department, Zealand University Hospital, Roskilde, Denmark. 6. Department of Radiation Oncology, Mayo Clinic, Scottsdale, AZ, U.S.A.
Abstract
BACKGROUND/AIM: A considerable number of patients with lung cancer are scheduled for definitive or adjuvant radiotherapy. Prevalence and potential risk factors of pre-radiotherapy sleep disturbances were evaluated. PATIENTS AND METHODS: Nineteen factors were retrospectively investigated for associations with pre-radiotherapy sleep disturbances in 77 lung cancer patients. Factors included COVID-19 pandemic; age; gender; performance score; comorbidity index; history of another malignancy; distress score; number of emotional, physical or practical problems; patient's request for psychological support; histology; tumor stage; upfront surgery; chemotherapy; and type of radiotherapy. RESULTS: Thirty-one patients (40.3%) reported sleep disturbances that were significantly associated with distress score 6-10 (p=0.019), ≥2 emotional problems (p=0.001), ≥5 physical problems (p<0.001), and request for psychological support (p=0.006). Trends were found for female gender (p=0.064) and stereotactic body radiation therapy (p=0.057). CONCLUSION: Many lung cancer patients assigned to radiotherapy reported sleep disturbances. Risk factors can be used to identify patients in need of psychological support already before treatment.
BACKGROUND/AIM: A considerable number of patients with lung cancer are scheduled for definitive or adjuvant radiotherapy. Prevalence and potential risk factors of pre-radiotherapy sleep disturbances were evaluated. PATIENTS AND METHODS: Nineteen factors were retrospectively investigated for associations with pre-radiotherapy sleep disturbances in 77 lung cancer patients. Factors included COVID-19 pandemic; age; gender; performance score; comorbidity index; history of another malignancy; distress score; number of emotional, physical or practical problems; patient's request for psychological support; histology; tumor stage; upfront surgery; chemotherapy; and type of radiotherapy. RESULTS: Thirty-one patients (40.3%) reported sleep disturbances that were significantly associated with distress score 6-10 (p=0.019), ≥2 emotional problems (p=0.001), ≥5 physical problems (p<0.001), and request for psychological support (p=0.006). Trends were found for female gender (p=0.064) and stereotactic body radiation therapy (p=0.057). CONCLUSION: Many lung cancer patients assigned to radiotherapy reported sleep disturbances. Risk factors can be used to identify patients in need of psychological support already before treatment.
Authors: Jimmie C Holland; Barbara Andersen; William S Breitbart; Luke O Buchmann; Bruce Compas; Teresa L Deshields; Moreen M Dudley; Stewart Fleishman; Caryl D Fulcher; Donna B Greenberg; Carl B Greiner; George F Handzo; Laura Hoofring; Charles Hoover; Paul B Jacobsen; Elizabeth Kvale; Michael H Levy; Matthew J Loscalzo; Randi McAllister-Black; Karen Y Mechanic; Oxana Palesh; Janice P Pazar; Michelle B Riba; Kristin Roper; Alan D Valentine; Lynne I Wagner; Michael A Zevon; Nicole R McMillian; Deborah A Freedman-Cass Journal: J Natl Compr Canc Netw Date: 2013-02-01 Impact factor: 11.908