Literature DB >> 3469644

On the translocation of proteins across membranes.

S J Singer, P A Maher, M P Yaffe.   

Abstract

Many proteins of intracellular organelles are first synthesized in the cytoplasm and are then specifically transferred across the membranes of the organelles. On the assumption that these transfers all occur by the same basic mechanism, we enumerate the rather stringent requirements that the mechanism must satisfy. A unitary molecular mechanism is then proposed that meets these requirements.

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Year:  1987        PMID: 3469644      PMCID: PMC304352          DOI: 10.1073/pnas.84.4.1015

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  52 in total

1.  Translocation of secretory proteins across the microsomal membrane occurs through an environment accessible to aqueous perturbants.

Authors:  R Gilmore; G Blobel
Journal:  Cell       Date:  1985-09       Impact factor: 41.582

2.  The Croonian Lecture, 1968. The haemoglobin molecule.

Authors:  M F Perutz
Journal:  Proc R Soc Lond B Biol Sci       Date:  1969-05-20

3.  Is there a single pathway for the folding of a polypeptide chain?

Authors:  S C Harrison; R Durbin
Journal:  Proc Natl Acad Sci U S A       Date:  1985-06       Impact factor: 11.205

4.  Dual functions of the signal peptide in protein transfer across the membrane.

Authors:  J Coleman; M Inukai; M Inouye
Journal:  Cell       Date:  1985-11       Impact factor: 41.582

5.  Requirement of a membrane potential for the posttranslational transfer of proteins into mitochondria.

Authors:  M Schleyer; B Schmidt; W Neupert
Journal:  Eur J Biochem       Date:  1982-06-15

6.  Translocation of domains of nascent periplasmic proteins across the cytoplasmic membrane is independent of elongation.

Authors:  L L Randall
Journal:  Cell       Date:  1983-05       Impact factor: 41.582

Review 7.  Mechanisms of protein localization.

Authors:  T J Silhavy; S A Benson; S D Emr
Journal:  Microbiol Rev       Date:  1983-09

Review 8.  How mitochondria import proteins.

Authors:  R Hay; P Böhni; S Gasser
Journal:  Biochim Biophys Acta       Date:  1984-01-27

9.  Trans-membrane translocation of proteins. The direct transfer model.

Authors:  G von Heijne; C Blomberg
Journal:  Eur J Biochem       Date:  1979-06

10.  Intracellular sorting of alcohol dehydrogenase isoenzymes in yeast: a cytosolic location reflects absence of an amino-terminal targeting sequence for the mitochondrion.

Authors:  A P van Loon; E T Young
Journal:  EMBO J       Date:  1986-01       Impact factor: 11.598

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  28 in total

1.  Ionic permeability of the mitochondrial outer membrane.

Authors:  O Moran; M Sciancalepore; G Sandri; E Panfili; R Bassi; C Ballarin; M C Sorgato
Journal:  Eur Biophys J       Date:  1992       Impact factor: 1.733

Review 2.  The structure and function of membranes--personal memoir.

Authors:  S J Singer
Journal:  J Membr Biol       Date:  1992-07       Impact factor: 1.843

Review 3.  Structure, function, and biogenesis of SecY, an integral membrane protein involved in protein export.

Authors:  K Ito
Journal:  J Bioenerg Biomembr       Date:  1990-06       Impact factor: 2.945

Review 4.  Intracellular sterol trafficking.

Authors:  M P Reinhart
Journal:  Experientia       Date:  1990-06-15

Review 5.  Subunit assembly and functional maturation of Na,K-ATPase.

Authors:  K Geering
Journal:  J Membr Biol       Date:  1990-05       Impact factor: 1.843

Review 6.  Protein translocation in vitro: biochemical characterization of genetically defined translocation components.

Authors:  J Fandl; P C Tai
Journal:  J Bioenerg Biomembr       Date:  1990-06       Impact factor: 2.945

7.  Degradation of a signal peptide by protease IV and oligopeptidase A.

Authors:  P Novak; I K Dev
Journal:  J Bacteriol       Date:  1988-11       Impact factor: 3.490

Review 8.  Microinjected ribonuclease A as a probe for lysosomal pathways of intracellular protein degradation.

Authors:  J F Dice
Journal:  J Protein Chem       Date:  1988-04

Review 9.  Modulation of inner mitochondrial membrane channel activity.

Authors:  K W Kinnally; Y N Antonenko; D B Zorov
Journal:  J Bioenerg Biomembr       Date:  1992-02       Impact factor: 2.945

10.  Voltage activation of heart inner mitochondrial membrane channels.

Authors:  D B Zorov; K W Kinnally; H Tedeschi
Journal:  J Bioenerg Biomembr       Date:  1992-02       Impact factor: 2.945

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