| Literature DB >> 3469644 |
S J Singer, P A Maher, M P Yaffe.
Abstract
Many proteins of intracellular organelles are first synthesized in the cytoplasm and are then specifically transferred across the membranes of the organelles. On the assumption that these transfers all occur by the same basic mechanism, we enumerate the rather stringent requirements that the mechanism must satisfy. A unitary molecular mechanism is then proposed that meets these requirements.Mesh:
Substances:
Year: 1987 PMID: 3469644 PMCID: PMC304352 DOI: 10.1073/pnas.84.4.1015
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205