Literature DB >> 3468119

Sensitivity and specificity of commercial ELISA kits for screening anti-LAV/HTLV III.

L G Gürtler, J Eberle, B Lorbeer, F Deinhardt.   

Abstract

Two panels consisting of 236 and 258 anti-LAV/HTLV III positive and 64 and 50 negative sera, respectively (determined in Western blots), were tested with 8 different, commercially available ELISA test kits for detecting LAV/HTLV III antibodies (Abbott, Dupont, Electro-Nucleonics, Litton, Organon, Pasteur, Sorin, Wellcome). Positive sera were selected for levels of antibodies ranging from average to very high, and the negative sera included both negative sera and sera with antibodies to cellular components such as HLA antigens or nuclear membranes. In examination of the 2 panels, the sensitivity of the tests ranged from 97.2 to 100%, and the specificity from 70.0 to 100%. No test was ideal.

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Year:  1987        PMID： 3468119     DOI： 10.1016/0166-0934(87)90044-9

Source DB:  PubMed          Journal:  J Virol Methods        ISSN： 0166-0934            Impact factor:   2.014


  12 in total

1.  New sensitive and specific assay for human immunodeficiency virus antibodies using labeled recombinant fusion protein and time-resolved fluoroimmunoassay.

Authors:  H Siitari; P Turunen; J Schrimsher; M Nunn
Journal:  J Clin Microbiol       Date:  1990-09       Impact factor: 5.948

2.  Detection of antibodies to human immunodeficiency virus type I by using synthetic peptides and time-resolved fluoroimmunoassay (TR-FIA).

Authors:  V R Lombardi; O Libonatti; M Alimandi; I Ansotegui; G Scarlatti; V Moschese; H Wigzell; P Rossi
Journal:  Eur J Epidemiol       Date:  1992-03       Impact factor: 8.082

3.  Evaluation of enzyme-linked immunoassay systems for detection of human immunodeficiency virus type 1 antibody from filter paper disks impregnated with whole blood.

Authors:  J L Beebe; L C Briggs
Journal:  J Clin Microbiol       Date:  1990-04       Impact factor: 5.948

4.  Prevalence of antibodies to hepatitis C virus (HCV) in haemophiliacs.

Authors:  W Schramm; M Roggendorf; F Rommel; R Kammerer; H Pohlmann; R Rasshofer; L Gürtler; F Deinhardt
Journal:  Blut       Date:  1989-10

5.  A new subtype of human immunodeficiency virus type 1 (MVP-5180) from Cameroon.

Authors:  L G Gürtler; P H Hauser; J Eberle; A von Brunn; S Knapp; L Zekeng; J M Tsague; L Kaptue
Journal:  J Virol       Date:  1994-03       Impact factor: 5.103

6.  Comparison of five commercial enzyme-linked immunosorbent assays and Western immunoblotting for human immunodeficiency virus antibody detection in serum samples from Central Africa.

Authors:  F Behets; A Disasi; R W Ryder; K Bishagara; P Piot; M Kashamuka; M Kamenga; N Nzila; M Laga; G Vercauteren
Journal:  J Clin Microbiol       Date:  1991-10       Impact factor: 5.948

7.  AIDS: no association with the genetic systems GC (D-binding protein), ORM (orosomucoid = alpha-1-acid glycoprotein), and A2HS (alpha-2-HS-glycoprotein).

Authors:  H Cleve; S Weidinger; L G Gürtler; F Deinhardt
Journal:  Infection       Date:  1988       Impact factor: 3.553

8.  [Virus-specific antibody profile in various stages of HIV-1 infection. Western blot analysis of 170 patients].

Authors:  C Schulte; M Meurer; O Braun-Falco; M Held; M Fröschl
Journal:  Klin Wochenschr       Date:  1988-06-01

9.  Multicentre study for diagnostic evaluation of an assay for simultaneous detection of antibodies to HIV-1, HIV-2 and HIV-1 subtype 0 (HIV-0).

Authors:  P Bachmann; J Beyer; S Brust; W Engelhardt; L G Gürtler; K O Habermehl; A Karakassopoulos; U Michl; A Mühlbacher; M Stöffler-Meilicke
Journal:  Infection       Date:  1995 Sep-Oct       Impact factor: 3.553

10.  Multicenter evaluation of a fully automated screening test, VIDAS HIV 1 + 2, for antibodies to human immunodeficiency virus types 1 and 2.

Authors:  J M Azevedo-Pereira; M H Lourenço; F Barin; R Cisterna; F Denis; P Moncharmont; R Grillo; M O Santos-Ferreira
Journal:  J Clin Microbiol       Date:  1994-10       Impact factor: 5.948
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